Comparison of four formulas for the intraocular lens power prediction

Abstract Purpose To assess the accuracy of four formulas for intraocular lens (IOL) power prediction in cataractous eyes. METHODS In this prospective study, 51 eyes of 38 cataractous patients with an axial length (AL) between 24.0 and 26.0 mm were included. Preoperatively, Topolyzer, IOLMaster and A-scan were performed. At least 3 months after the surgery, subjective refraction was conducted. Haigis, SRK/T, Hoffer Q and Holladay 1 formulas based on ocular biometry from A-scan combining Topolyzer, IOLMaster combining Topolyzer and IOLMaster only were applied for IOL power prediction. RESULTS The four formulas based on biometry from IOLMaster combining Topolyzer and IOLMaster only performed better than those based on biometry from A-scan combining Topolyzer. Based on biometry from IOLMaster combining Topolyzer, Haigis formula had a mean NEs of -0.03 ± 0.71 D and a mean AEs of 0.53 ± 0.47 D, SRK/T formula had a mean NEs of 0.37 ± 0.72 D and a mean AEs of 0.63 ± 0.50 D, Hoffer Q formula had a mean NEs of 0.05 ± 0.62 D and a mean AEs of 0.43 ± 0.44 D, Holladay 1 formula had a mean NEs of 0.32 ± 0.63 D and a mean AEs of 0.54 ± 0.45 D. Based on biometry from IOLMaster only, Haigis formula had a mean NEs of 0.02 ± 0.54 D and a mean AEs of 0.41 ± 0.36 D, SRK/T formula had a mean NEs of 0.41 ± 0.54 D and a mean AEs of 0.52 ± 0.43 D, Hoffer Q formula had a mean NEs of 0.05 ± 0.58 D and a mean AEs of 0.36 ± 0.46 D, Holladay 1 formula had a mean NEs of 0.32 ± 0.45 D and a mean AEs of 0.43 ± 0.35 D. CONCLUSIONS Haigis and Hoffer Q formulas performed slightly better than SRK/T and Holladay 1 formulas. Therefore, for cataractous patients with moderate AL, all four formulas based the biometry from IOLMaster combining Topolyzer and IOLMaster only can be used for the prediction of IOL power, and the Haigis and Hoffer Q formulas are particularly recommended.