Secondary Glaucoma in Intraocular Tumors

The most common malignant intraocular tumors in adults include uveal melanoma, intraocular metastatic tumors, leukemic infiltrates, and intraocular lymphoma. </br>Elevated intraocular pressure occurs in approximately 5% of eyes with intraocular tumors. Glaucoma may develop secondary to intraocular tumors in adults through various mechanisms such as drainage angle infiltration, angle closure, or neovascularization. These tumors may be primary (e.g., uveal melanoma) or metastatic. Unilateral or treatment-resistant glaucoma should prompt suspicion of an intraocular tumor. The type and location of an intraocular tumor determine the likelihood of elevated intraocular pressure. </br>Based on literature data and our own cases, the paper reviews the mechanisms of secondary glaucoma development in the most common intraocular tumors in adults.