Javascript must be enabled to continue!
Total arch replacement versus proximal aortic replacement in acute type A aortic dissection: Aggressive versus conservative
View through CrossRef
Background: Acute type A aortic dissection (ATAAD) is a life-threatening
medical condition requiring urgent surgical attention. It is estimated
that 50% of ATAAD die within 24 hours of onset, with the mortality rate
is increasing by 1-2% every additional hour without prompt
intervention. A variety of ATAAD surgical repair techniques exist which
has sparked controversy within the literature, with the main two
strategies being proximal aortic replacement (PAR) and total arch
replacement (TAR). Nevertheless, the question of which of these two
strategies if the more optimal is still debatable. Aims: This commentary
aims to discuss the recent study by Sa and colleagues which presents a
pooled analysis of Kaplan-Meier-derived individual patient data from
studies with follow-up comparing aggressive (TAR) and conservative (PAR)
approaches to manage ATAAD patients. Methods: A comprehensive literature
search was performed using multiple electronic databases including
PubMed, Ovid, Google Scholar, EMBASE and Scopus in order to collate the
relevant research evidence. Results: The more aggressive TAR approach
for treating ATAAD seems to yield more favourable results including more
optimal long-term survival as well as a lower need for reoperation. The
frozen elephant trunk (FET) technique can be considered the mainstay TAR
technique. Conclusion: It is valid to conclude that TAR with FET is the
superior strategy for managing ATAAD patients.
Title: Total arch replacement versus proximal aortic replacement in acute type A aortic dissection: Aggressive versus conservative
Description:
Background: Acute type A aortic dissection (ATAAD) is a life-threatening
medical condition requiring urgent surgical attention.
It is estimated
that 50% of ATAAD die within 24 hours of onset, with the mortality rate
is increasing by 1-2% every additional hour without prompt
intervention.
A variety of ATAAD surgical repair techniques exist which
has sparked controversy within the literature, with the main two
strategies being proximal aortic replacement (PAR) and total arch
replacement (TAR).
Nevertheless, the question of which of these two
strategies if the more optimal is still debatable.
Aims: This commentary
aims to discuss the recent study by Sa and colleagues which presents a
pooled analysis of Kaplan-Meier-derived individual patient data from
studies with follow-up comparing aggressive (TAR) and conservative (PAR)
approaches to manage ATAAD patients.
Methods: A comprehensive literature
search was performed using multiple electronic databases including
PubMed, Ovid, Google Scholar, EMBASE and Scopus in order to collate the
relevant research evidence.
Results: The more aggressive TAR approach
for treating ATAAD seems to yield more favourable results including more
optimal long-term survival as well as a lower need for reoperation.
The
frozen elephant trunk (FET) technique can be considered the mainstay TAR
technique.
Conclusion: It is valid to conclude that TAR with FET is the
superior strategy for managing ATAAD patients.
Related Results
Accuracy of D-Dimers to diagnose aortic dissection and its different types keeping CT angiogram as gold standard.
Accuracy of D-Dimers to diagnose aortic dissection and its different types keeping CT angiogram as gold standard.
Objective: To determine diagnostic accuracy of D-dimers levels to diagnose aortic dissection and its different types keeping computed tomographic angiogram as gold standard. Study ...
Assessment of Aortic Arch Morphology for Endovascular Interventions
Assessment of Aortic Arch Morphology for Endovascular Interventions
Abstract
Introduction
: The aim of this study was to retrospectively classify the aorta according to the location of the supra-aortic vessels and analyze the aortic arch a...
Aortic Aneurysm
Aortic Aneurysm
Aortic diseases are relatively rare but are associated with high morbidity and mortality. Emergency physicians (EPs) should consider aortic disease in all patients with pain in the...
Aortic Aneurysm
Aortic Aneurysm
Aortic diseases are relatively rare but are associated with high morbidity and mortality. Emergency physicians (EPs) should consider aortic disease in all patients with pain in the...
Aortic dissection in Siriraj patients: Computed tomography findings
Aortic dissection in Siriraj patients: Computed tomography findings
Background: CTA has replaced angiography in both diagnosis and evaluation of aortic dissection. Most findings are associated with true and false lumens which account for the most i...
Clinical Features of Pregnancy-Associated Aortic Dissection and Pregnancy Outcomes
Clinical Features of Pregnancy-Associated Aortic Dissection and Pregnancy Outcomes
Abstract
Background
Pregnancy complicated by aortic dissection is a rare and severe condition. Due to limited clinical experience, there are currently no standardiz...
Risk factors for target vessel endoleaks after physician-modified fenestrated or branched endovascular aortic arch repair: A retrospective study
Risk factors for target vessel endoleaks after physician-modified fenestrated or branched endovascular aortic arch repair: A retrospective study
ObjectiveFenestrated or branched endovascular aortic arch repair (fb-arch repair) is an effective option for treating complex aortic arch lesions, including thoracic aortic aneurys...
Decreased expression of fibulin-4 in aortic wall of aortic dissection
Decreased expression of fibulin-4 in aortic wall of aortic dissection
In this research, we will examine the expression of Fibulin-4 in aortic wall to find out its role in aortic dissection development. The samples of aortic wall were obtained from 10...

