Influence of cerium dioxide nanoparticles on biochemical indicators in the organism of broiler chicken

At present, nanotechnology is taking the leading role in various industries, medicine, and agriculture all over the world. Fundamentally different properties are inherent in nanoparticles, in particular, a high capacity for accumulation in living organisms by overcoming biobarriers, increasing bioavailability and binding with the main components of cells. The article studies the peculiarities of the influence of cerium dioxide nanoparticles on metabolic pathways in the body of broiler chickens. The data on the use of metal nanoparticles, in particular, a material based on cerium, as an alternative to feed antibiotics for increasing the productivity of livestock and poultry farming has been analyzed. The aim of this work was to investigate the effect of cerium dioxide nanoparticles on the biochemical blood profile of chickens with meat production. For the studies carried out at the Research Institute of Ecology and Biotechnology of the Bila Tserkva NAU, a new multifunctional antioxidant was used - nanodispersed cerium dioxide, developed by the D. K. Zabolotny Institute of Microbiology and Virology of the NASU, Ukraine. For the scientific and economic experience there were formed 3 groups of broilers of the ROSS 308 cross according to the principle of analogous groups (control and 2 experimental groups, 100 heads each). For 58 days, the experimental groups of birds with drinking water were added nanodispersed cerium dioxide at a dose of 8.6 mg/l during the first 14 days. Course was repeated after 7 (group 1) and 14 days (group 2) breaks. As a result of the studies, it was found that the blood parameters of broilers, characterizing the main types of metabolism were within the physiological norm. There was a tendency to activation of lipid and protein metabolism, which contributed to the intensification of the growth of young animals. The use of nanodispersed cerium dioxide as a promising material for increasing the productivity of poultry farming and as an alternative to feed antibiotics is argued. In further studies, it is advisable to study the action of cerium dioxide nanoparticles to study all possible mechanisms of its biological activity.