Feasibility study of a peristaltic pump as a power source in an extracorporeal liver perfusion device

Abstract With the increasing number of patients with end-stage liver disease in recent years, liver transplantation plays an indispensable role in the treatment of patients with end-stage liver disease. Recently there has been a large increase in the number of organs from organ donation sources after the death of citizens, for which a large number of marginal hepatic donors, such as elderly donor livers and fatty liver donor livers, have been generated, and in order to alleviate and improve the utilisation of these marginal hepatic livers, extracorporeal hepatic perfusion devices have come into being, but at present, the cost of a single extracorporeal perfusion session is too high. Here we show our self-developed a multi-membrane extracorporeal liver perfusion device using a peristaltic pump as the power unit with a multi-mode control system, which reduces the cost of a single extracorporeal perfusion to a greater extent, in order to explore a more time-consuming extracorporeal perfusion device to improve the marginal hepatic.