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A COMPARATIVE STUDY OF 0.5% BUPIVACAINE HEAVY VERSUS 0.5% BUPIVACAINE HEAVY PLUS DEXMEDETOMIDINE IN SPINAL ANESTHESIA FOR INFRAUMBILICAL SURGERIES: A PROSPECTIVE, RANDOMIZED STUDY
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Background: Ensuring appropriate intraoperative anesthesia and postoperative pain management for infraumbilical surgery remains a signicant
challenge. However, the use of adjuvants such as dexmedetomidine in spinal anesthesia has been shown to extend the duration of pain relief in the
postoperative period. Recent studies have demonstrated substantial improvements in postoperative pain management and stable intraoperative
conditions when dexmedetomidine is used as an adjuvant in spinal anesthesia. To assess the efcacy of adding dexmedetomidine to bupivacaine
heavy in spinal block compared to using plain bupivacaine heavy in patients undergoing infraumbilical surgeries, a prospective, randomized study
was conducted. Sixty patients scheduled for infraumbilical surgeries were randomly assigned to two Methods: groups: one group received
dexmedetomidine along with 0.5% bupivacaine heavy, and the other group received plain 0.5% bupivacaine heavy in equal volume. The Results:
beginning of sensory blockade in Group C occurred at (151.66 ± 15.33 seconds) and in Group D at (128.66 ± 11.36 seconds), with a statistically
signicant difference (p < 0.001). In Group C, the peak sensory block was reached at (9.41 ± 0.56) and in Group D at (7.33 ± 0.73). The highest
dermatomal sensory level observed in Group C was (6.8 ± 1.09 minutes) and in Group D was (5.96 ± 0.67). The onset of motor block in Group C
was at (178 ± 16.48 seconds) and in Group D and (140 ± 13.89 minutes). Complete motor block was achieved in Group C at (8.6 ± 0.57 minutes) and
in Group D at (6.67 ± 0.63 minutes) (p < 0.001). The regression of sensory block to two segments in Group C was (92.83 ± 8.37 minutes) and in
Group D (146.83 ± 9.14 minutes) with p < 0.001). The regression to T12 in Group C was (139.5 ± 13.60) and in Group D at (208.116 ± 16.21).
Complete recovery of motor block was observed in Group C (179.16 ± 14.62) and Group D (265.66 ± 19.24). The total duration of analgesia in
Group C was (187.5 ± 15.07 minutes) and in Group D was (301 ± 25.77 minutes). Group D exhibited a r Conclusion: apid onset of sensory and
motor block, and the duration of the motor and sensory block was signicantly longer than in Group C. The total analgesia duration in Group D was
also longer. Moreover, adding dexmedetomidine to spinal anesthesia provided better surgical conditions and analgesia compared to plain
bupivacaine.
World Wide Journals
Title: A COMPARATIVE STUDY OF 0.5% BUPIVACAINE HEAVY VERSUS 0.5% BUPIVACAINE HEAVY PLUS DEXMEDETOMIDINE IN SPINAL ANESTHESIA FOR INFRAUMBILICAL SURGERIES: A PROSPECTIVE, RANDOMIZED STUDY
Description:
Background: Ensuring appropriate intraoperative anesthesia and postoperative pain management for infraumbilical surgery remains a signicant
challenge.
However, the use of adjuvants such as dexmedetomidine in spinal anesthesia has been shown to extend the duration of pain relief in the
postoperative period.
Recent studies have demonstrated substantial improvements in postoperative pain management and stable intraoperative
conditions when dexmedetomidine is used as an adjuvant in spinal anesthesia.
To assess the efcacy of adding dexmedetomidine to bupivacaine
heavy in spinal block compared to using plain bupivacaine heavy in patients undergoing infraumbilical surgeries, a prospective, randomized study
was conducted.
Sixty patients scheduled for infraumbilical surgeries were randomly assigned to two Methods: groups: one group received
dexmedetomidine along with 0.
5% bupivacaine heavy, and the other group received plain 0.
5% bupivacaine heavy in equal volume.
The Results:
beginning of sensory blockade in Group C occurred at (151.
66 ± 15.
33 seconds) and in Group D at (128.
66 ± 11.
36 seconds), with a statistically
signicant difference (p < 0.
001).
In Group C, the peak sensory block was reached at (9.
41 ± 0.
56) and in Group D at (7.
33 ± 0.
73).
The highest
dermatomal sensory level observed in Group C was (6.
8 ± 1.
09 minutes) and in Group D was (5.
96 ± 0.
67).
The onset of motor block in Group C
was at (178 ± 16.
48 seconds) and in Group D and (140 ± 13.
89 minutes).
Complete motor block was achieved in Group C at (8.
6 ± 0.
57 minutes) and
in Group D at (6.
67 ± 0.
63 minutes) (p < 0.
001).
The regression of sensory block to two segments in Group C was (92.
83 ± 8.
37 minutes) and in
Group D (146.
83 ± 9.
14 minutes) with p < 0.
001).
The regression to T12 in Group C was (139.
5 ± 13.
60) and in Group D at (208.
116 ± 16.
21).
Complete recovery of motor block was observed in Group C (179.
16 ± 14.
62) and Group D (265.
66 ± 19.
24).
The total duration of analgesia in
Group C was (187.
5 ± 15.
07 minutes) and in Group D was (301 ± 25.
77 minutes).
Group D exhibited a r Conclusion: apid onset of sensory and
motor block, and the duration of the motor and sensory block was signicantly longer than in Group C.
The total analgesia duration in Group D was
also longer.
Moreover, adding dexmedetomidine to spinal anesthesia provided better surgical conditions and analgesia compared to plain
bupivacaine.
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