Evaluation of Corneal Biomechanical Properties by Corvis ST in Saudi Females with Dry Eye Disorder

Aim: This study compared corneal biomechanics in patients with Dry Eye Disorder (DED) and age-matched control subjects using the Corvis ST. Furthermore, the current study correlated the parameters of DED with alterations in the corneal biomechanical properties. Methods: Sixty eyes participated in this prospective case-control study. They were divided into 2 groups: Dry eye (???? = 40 eyes) and control eye (???? = 20 eyes) groups. The age range was 20-39 years. Each subject underwent a comprehensive ophthalmologic examination. In addition, the Non-Invasive Tear Break-Up Time (NIBUT) and Tear Meniscus Height (TMH) were measured using the OCULUS Keratograph non-invasive ocular surface analyzer. All participants completed an Ocular Surface Disease Index (OSDI) questionnaire to evaluate the dry eye symptoms before conducting the study. The corneal biomechanical parameters and central corneal thickness were measured for all eyes using Corvis ST with an automatic release mode. Results: This study found a significant difference in only one parameter (A1 Length) between the 2 groups. The dry eye group had a significantly higher A1 length (2.31 ± 0.32 mm) compared to the control group (2.10 ± 0.34 mm) (Mann-Whitney ????=274.50, ????=0.049). However, this study demonstrated no correlation between the parameters of DED (NIBUT, TMH and OSDI) and the corneal biomechanical properties. Conclusion: This study found that the dry eye group exhibited a significantly higher A1 length compared with the control group, suggesting a potential trend toward altered corneal deformation behavior in dry eye disease.  However, this study did not confirm any significant correlation between DED parameters and corneal biomechanics.