Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
YANGI 1,2,4-TRIAZOL VA 1,2,4-TRIAZOL–TIAZIDIN HOSILALARINING SINTEZI VA REAKSION QOBILIYATI
View through CrossRef
Ushbu ishda 1,2,4-triazcccol va 1,2,4-triazol-tiazidin hosilalari sintezi, ularning reaksion qobiliyati va tuzilishi o‘rganildi. Tadqiqotlar natijasida N-atsil-1,3,4-oksadiazol hosilalari gidrazin gidrat ishtirokida yuqori unum bilan 1,2,4-triazol hosilalariga aylantirildi. Shuningdek, epilepsiyaga qarshi faoliyat ko‘rsatadigan 4-(6-fenil-7H-[1,2,4]-triazol-[3,4-b]-[1,3,4]-tiazidin-3-il)anilin molekulasi asosida turli N-atsil hosilalari sintez qilindi. Birikmalar 1H YaMR va IQ spektral usullari yordamida tuzilishi tasdiqlandi. Sintez qilingan birikmalar yuqori biofaollik va farmakologik potensialga ega bo‘lib, ularning antibakterial, zamburug‘larga qarshi va boshqa biologik faolliklari uchun istiqbolli modda sifatida qaraladi. Ushbu natijalar farmatsevtik kimyo va biokimyoviy tadqiqotlarda yangi yo‘nalishlarni rivojlantirishga xizmat qiladi.
National University of Uzbekistan
Title: YANGI 1,2,4-TRIAZOL VA 1,2,4-TRIAZOL–TIAZIDIN HOSILALARINING SINTEZI VA REAKSION QOBILIYATI
Description:
Ushbu ishda 1,2,4-triazcccol va 1,2,4-triazol-tiazidin hosilalari sintezi, ularning reaksion qobiliyati va tuzilishi o‘rganildi.
Tadqiqotlar natijasida N-atsil-1,3,4-oksadiazol hosilalari gidrazin gidrat ishtirokida yuqori unum bilan 1,2,4-triazol hosilalariga aylantirildi.
Shuningdek, epilepsiyaga qarshi faoliyat ko‘rsatadigan 4-(6-fenil-7H-[1,2,4]-triazol-[3,4-b]-[1,3,4]-tiazidin-3-il)anilin molekulasi asosida turli N-atsil hosilalari sintez qilindi.
Birikmalar 1H YaMR va IQ spektral usullari yordamida tuzilishi tasdiqlandi.
Sintez qilingan birikmalar yuqori biofaollik va farmakologik potensialga ega bo‘lib, ularning antibakterial, zamburug‘larga qarshi va boshqa biologik faolliklari uchun istiqbolli modda sifatida qaraladi.
Ushbu natijalar farmatsevtik kimyo va biokimyoviy tadqiqotlarda yangi yo‘nalishlarni rivojlantirishga xizmat qiladi.
Related Results
KARBON QAZININ UTİLİZASİYASI İLƏ ETİLENKARBONATIN SİNTEZİ ÜÇÜN YENİ ZN-FENOLYAT KATALİZATORLARI
KARBON QAZININ UTİLİZASİYASI İLƏ ETİLENKARBONATIN SİNTEZİ ÜÇÜN YENİ ZN-FENOLYAT KATALİZATORLARI
Karbon qazı (CO2) enerji mənbələri kimi istifadə olunan təbii ehtiyatların (neft, qaz, daş kömür və s.) və eləcə də neft-kimya sənayesinin müxtəlif proseslərinin tullantılarının ya...
3,3'-DISULFANIDILBIS (1H-1,2,4-TRIAZOL-5-AMIN) SINTEZI
3,3'-DISULFANIDILBIS (1H-1,2,4-TRIAZOL-5-AMIN) SINTEZI
Ishdan maqsad 3-amino-5-merkapto-1,2,4-triazoldan yangi organik modda 3,3'-disulfanidilbis(1H-1,2,4-triazol-5-amin)ni sintez qilishdir. Maqolada 3-amino-5-merkapto-1,2,4-triazolnin...
Pengembangan Budaya Organisasi Lembaga Pendidikan (Studi Kasus di TK Aisyiyah Jemundo)
Pengembangan Budaya Organisasi Lembaga Pendidikan (Studi Kasus di TK Aisyiyah Jemundo)
Organisasii merupakani suatui sistemi yangi didalamnyai terdapati berbagaii unsuri yangi salingi keterkaitani antarai satui samai lainnya.i Budayai organisasii mengandungi keseluru...
Synthesis of some new five membered heterocycles, a facile synthesis of oxazolidinones
Synthesis of some new five membered heterocycles, a facile synthesis of oxazolidinones
Abstractmagnified imageThe synthesis and structural properties of two kinds of thiosemicarbazide derivatives (2a‐c and 3a‐c) and one kind of semicarbazide derivatives (4a, 4b) have...
Synthesis, characterization and antioxidant activity of sulfonyl-1H-1,2,3-triazoles
Synthesis, characterization and antioxidant activity of sulfonyl-1H-1,2,3-triazoles
3-methoxy-4-((1-tosyl-1H-1,2,3-triazol-4-yl)methoxy)benzaldehyde (3), 4-((1-(ethylsulfonyl)-1H-1,2,3-triazol-4-yl) methoxy) benzaldehyde (6), 4-((1-((4-chloro phenyl) sulfonyl)-1H-...
BENZIMIDAZOL HOSILALARI VA 3D-METALLAR BILAN KOMPLEKS BIRIKMALARI: SINTEZI, TUZILISHI VA XOSSALARI
BENZIMIDAZOL HOSILALARI VA 3D-METALLAR BILAN KOMPLEKS BIRIKMALARI: SINTEZI, TUZILISHI VA XOSSALARI
Benzimidazol hosilalari azot tutuvchi geterosiklik birikmalar sinfiga mansub bo‘lib, yuqori biologik faolligi va kuchli koordinatsion qobiliyati sababli farmatsevtika hamda koordin...
Propargyl Alcohol‐Derived 1,2,3‐Triazoles Demonstrate Antiplasmodial Activity
Propargyl Alcohol‐Derived 1,2,3‐Triazoles Demonstrate Antiplasmodial Activity
Abstract
This research demonstrates computationally guided synthesis and antiplasmodial properties of novel propargyl alcohol‐derived 1,2,3‐triazoles namely: 1‐(3...
Elbekning yangi hikoyalari tahlili
Elbekning yangi hikoyalari tahlili
Maqolada milliy adabiyotimiz rivojiga munosib hissa qo‘shgan Elbekning hikoyanavislik mahorati haqida mulohaza yuritilgan. Ijodkor ning “Maorif va o‘qitg‘uvchi”, “Yer yuzi” kabi ju...