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Neurosteroids in the Retina
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Abstract: Steroids may have a powerful role in neuronal degeneration. Recent research has revealed that steroids may influence the onset and progression of some retinal disorders as well as neurodegenerative diseases and, as in brain, they accumulate in the retina via a local synthesis (neurosteroids) and metabolism of blood‐circulating steroid hormones. Their crucial role as neurodegenerative and neuroprotective agents has been also upheld in a retinal excitotoxic paradigm. These findings are reviewed especially from the emerging perspective that after an insult local changes in steroidogenic responses and consequent neurosteroid availability might turn out to be offensive or defensive cellular adaptations for the potentiation or prevention of neuronal death.
Title: Neurosteroids in the Retina
Description:
Abstract: Steroids may have a powerful role in neuronal degeneration.
Recent research has revealed that steroids may influence the onset and progression of some retinal disorders as well as neurodegenerative diseases and, as in brain, they accumulate in the retina via a local synthesis (neurosteroids) and metabolism of blood‐circulating steroid hormones.
Their crucial role as neurodegenerative and neuroprotective agents has been also upheld in a retinal excitotoxic paradigm.
These findings are reviewed especially from the emerging perspective that after an insult local changes in steroidogenic responses and consequent neurosteroid availability might turn out to be offensive or defensive cellular adaptations for the potentiation or prevention of neuronal death.
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Amaç:
Multiple skleroz (MS) hastalarında spektral optik koherens tomografi (OKT) ile
retina sinir lifi tabakası (RSLT)
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ABSTRACT
The retina is the sentient part of the eye, for which all the other textures are formed, and to which they may be said to be subservient. It is coextensive ...
Electrophysiological investigation of intact retina with soft printed organic neural interface
Electrophysiological investigation of intact retina with soft printed organic neural interface
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Objective. Understanding how the retina converts a natural image or an electrically stimulated one into neural firing patterns is the foc...
Retinitis Pigmentosa
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