Comprehensive analysis of the Anti-Inflammatory Activity of Champak Agad: An In-Vitro Study

Introduction: Prolonged inflammation can cause several health problems like cardiovascular diseases, arthritis, Crohn's disease, ulcerative colitis, and even cancer. Herbal anti-inflammatory formulations can be used to reduce the symptoms of inflammation as they have fewer side effects compared to synthetic drugs. One such herbal formulation is Champak Agad. This study was implemented to evaluate the possibility of Champak Agad's anti-inflammatory properties, which may be important for treating inflammatory diseases. Materials and Methods: Champak Agad was prepared according to the classical reference. The anti-inflammatory activity of Champak Agad was examined using an egg albumin protein denaturation assay in which the aqueous and alcoholic extract of the drug was used and diclofenac was used a standard drug. Result: In this study, the drug extracts showed varying degrees of inhibition according to different drug concentrations. This investigation demonstrated that the aqueous extract exhibited higher anti-inflammatory activity than the alcoholic extract. The aqueous extract showed an inhibition rate of 85% with a 200mg/ml drug dose and the inhibition rate observed with the alcoholic extract was 82% with a 200mg/ml drug dose. Discussion: By inhibiting protein denaturation in a concentration-dependent manner, the current study shows that Champak Agad extracts have strong anti-inflammatory properties.