The Effect Salvia Hispanica L Seed Extract on Stres Oxidatif in Rats with Overtraining

The purpose of this study was to determine: Increased oxidative stress as seen from malondialdehyde (MDA) and superoxide dismutase (SOD) levels after overtraining and the effect of chia seeds (Salvia Hispanica L) can reduce oxidative stress as seen from malondialdehyde (MDA) and superoxide dismutase (SOD) levels after overtraining. This study used a true experimental design method with a post-test only control group design. The number of samples in this study was 18 rats, then divided into 3 groups. The Control Group was only given standard feed, group I was given overtraining swimming start at 09.00 am - 12.00 noon every day for 28 days. and standard feed. Group KII was given overtraining swimming start at 09.00 am - 12.00 noon every day for 28 days and chia seed extract at a dose of 4.5 mg / kgBW. Blood serum samples were taken on the 29th day. Then the samples were examined by The Research Center of Biology and Chemistry Laboratory of IBL FK Unissula for SOD and MDA analysis. The results of this study indicate that SOD levels in the control group (4.83), group I (1.45), group II (3.11). The results of the ANOVA test were p<0.05. MDA levels in the control group (1.67), group I (1.91), group II (1.28) with ANOVA test results p<0.05. Thus overtraining can decrease SOD and increase MDA. Giving chia seed extract at a dose of 4.5 mg/kgBW can significantly overcome the decrease in SOD and increase MDA.