Evaluation of Antiulcer Activity of Different Extracts of Clitoria ternatea Leaves on Experimental Animals

We planned to evaluate the antiulcer effects of four different extract of Clitoria ternatea leaves.  Gastric lesions were induced in rats by oral administration of Indomethacin (10 ml/kg). The antiulcer activity of Petroleum ether, Chloroform, Methanol and aqueous extract of Clitoria ternatea leaves (200 mg/kg and 400 mg/kg body wt) was compared with standard drugs. The parameters studied were ulcer index, gastric juice volume and pH of gastric juice. Clitoria ternatea leaves showed a dose dependent curative ratio compared to ulcer control groups. Pretreatment with extract displayed significant antiulcer activity which is almost equal to that of the standard drug. The volume of acid secretion, and ulcer index were decreased and pH of the gastric juice was increased compared to ulcer control group. The petroleum extract showed maximum antiulcer activity compared to other extract.