Efficient Surfactant‐Mediated Photovoltaic Manipulation of fL‐Scale Aqueous Microdroplets for Diverse Optofluidic Applications on LiNbO3 Platform

AbstractThe electrodeless biocompatible manipulation of femtoliter‐scale aqueous microdroplets remains challenging. The appropriate isolation of electrostatic charges from femtoliter‐scale aqueous microdroplets is crucial for electrodeless optoelectronic manipulation based on space‐charge‐density modulation. Here, surfactant‐mediated photovoltaic manipulation is proposed, where the surfactant layers self‐assembled at the water–oil and oil–Lithium niobate interfaces are employed to isolate photovoltaic charges. The reduced electrostatic attenuation, remarkable hydrophobicity, and strong electrical breakdown suppression of the surfactant layers enable the stable and swift manipulation of femtoliter‐scale aqueous microdroplets using µW‐level laser in oil media. By virtue of the surfactant‐mediated photovoltaic manipulation, a controllable merging/touching/detaching switch of aqueous microdroplets by adjusting the laser illumination intensity and position is realized and the cascading biochemical operations and microreactions of aqueous microdroplets and microdroplet strings are demonstrated. To demonstrate its potential in photonic Micro‐Electro‐Mechanical‐System assemblies, the end coupling of a focused‐laser‐beam into a ZnO microrod leveraging the refraction effect occurring at the water/oil interface is demonstrated. Moreover, because of the selective permeability of the droplet‐interface‐bilayer developed between the touching microdroplets, in situ adjustment of the size of the microdroplets and the fluorescent solute contained in the microdroplets are achieved, aiming at constructing multicomponent fluorescent microdroplets with tunable whispering‐gallery‐mode characteristics.