Assessment of Antiulcer Activity of Ethanol Extract of Ficus religiosa Fruit in Pylorus Ligated and Aspirin induced Ulceration in Experimental Animals

Ficus religiosa is a medicinal plant and scientifically documented for the pharmacological activities like antidiabetic, anti-inflammatory, antipyretic, etc. The present study was planned to investigate the antiulcer activity of ethanol extract of Ficus religiosa fruit in pylorus ligated and aspirin induced ulceration in experimental animals. The ethanol extract of fruits of Ficus religiosa were prepared by maceration. The antiulcer activity of ethanol extract were evaluated by using pylorus ligated and aspirin induced ulceration models. The administration of ethanol extract of ethanol extract of Ficus religiosa at the dose of 200 mg/kg and 400 mg/kg significantly decreased the ulcer index, pH, gastric volume, free acidity and total acidity compared to control group. The findings proposed the antiulcer activity of ethanol extract of Ficus religiosa fruit.