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Evaluation of Yam (<i>Dioscorea sp.</i>) Starch and Arrowroot (<i>Maranta arundinacea</i>) Starch as Suspending Agent in Suspension
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The aim of our study was to evaluate the applicability of yam (Dioscorea sp.) starch and arrowroot (Maranta arundinacea) starch as suspending agents in suspension. Paracetamol was used as a model drug because of its low solubility. It was found that the optimal concentration as suspending agent in paracetamol suspension was in the range of 7-8% for yam starch and 5-6% for arrowroot starch. All formulations were stable within the period of study with pH of 5.4-6.9. These results were comparable to those obtained from the sodium carboxymethyl cellulose (sodium CMC) which is a common suspending agent. It could be concluded that yam starch and arrowroot starch showed suspending activity in paracetamol suspension and could be applied as commercial suspending agent.
Title: Evaluation of Yam (<i>Dioscorea sp.</i>) Starch and Arrowroot (<i>Maranta arundinacea</i>) Starch as Suspending Agent in Suspension
Description:
The aim of our study was to evaluate the applicability of yam (Dioscorea sp.
) starch and arrowroot (Maranta arundinacea) starch as suspending agents in suspension.
Paracetamol was used as a model drug because of its low solubility.
It was found that the optimal concentration as suspending agent in paracetamol suspension was in the range of 7-8% for yam starch and 5-6% for arrowroot starch.
All formulations were stable within the period of study with pH of 5.
4-6.
9.
These results were comparable to those obtained from the sodium carboxymethyl cellulose (sodium CMC) which is a common suspending agent.
It could be concluded that yam starch and arrowroot starch showed suspending activity in paracetamol suspension and could be applied as commercial suspending agent.
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