Phytochemical screening and evaluation of the antibacterial activity of extracts dichloromethane of total alkaloids from the leaves and roots of Guiera senegalensis (Combretaceae), a plant widely used in traditional Senegalese medicine

The present study involved extracting total alkaloids from the leaves and roots of Guiera senegalensis, a plant widely used in traditional Senegalese medicine. The results showed a low extraction rate. A phytochemical screening of these alkaloid extracts was carried out and the results showed the presence of alkaloids and a total absence of other chemical groups, in particular polyphenols, flavonoids, catechic tannins and gall tannins. Finally, antibacterial activity tests of alkaloid extracts from Guiera senegalensis leaves and roots were carried out on two pathogenic bacterial strains, namely "Gram +"Staphylococcus aureus and "Gram -" Escherichia coli. The results showed an antibacterial effect of the leaf extract on Staphylococcus aureus and Escherichia coli with a lower antibacterial power 4. The root alkaloid extract showed an antibacterial effect on Staphylococcus aureus with an even lower antibacterial potency 4. On the other hand, the root extract showed a bacteriostatic effect on Escherichia coli with an antibacterial potency greater than 4.