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Copper‐catalyzed Cyanation of Alkenyl Iodides

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Abstract Copper‐catalyzed vinylic version of the Rosenmund‐von Braun cyanation reaction was developed and provides an efficient entry to both E‐ and Z‐ polysubstituted alkenyl nitriles. The cyanation of (Z)‐1‐iodooct‐1‐ene described in this article is illustrative of this reaction which can be conveniently performed on a multi‐gram scale.
Title: Copper‐catalyzed Cyanation of Alkenyl Iodides
Description:
Abstract Copper‐catalyzed vinylic version of the Rosenmund‐von Braun cyanation reaction was developed and provides an efficient entry to both E‐ and Z‐ polysubstituted alkenyl nitriles.
The cyanation of (Z)‐1‐iodooct‐1‐ene described in this article is illustrative of this reaction which can be conveniently performed on a multi‐gram scale.

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