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Phytochemical analysis, antibacterial activity and antibiotic modifying action of Jatropha mollissima (Pohl.) Baill. (Euphorbiaceae)
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La aparición de cepas bacterianas resistentes y los efectos secundarios de sus fármacos disponibles han hecho investigar nuevos compuestos antibacterianos bioactivos. Jatropha mollissima es una planta endémica del bioma Caatinga, Brasil. Existen informes en la literatura de que esta especie tiene acción antioxidante, antibacteriana y antiproliferativa. El presente estudio tuvo como objetivo evaluar el potencial antibacteriano y modulador de J. mollissima contra cepas bacterianas multirresistentes. El perfil fitoquímico se obtuvo por cromatografía de gases junto con espectrometría de masas. J. mollissima mostró actividad antibacteriana moderada y moduló la actividad del antibiótico Norfloxacino, promoviendo una relación antagonista. Este fue el primer estudio de este tipo realizado con J. mollissima.
The emergence of resistant bacterial strains and the significant increase in side effects of currently available antibacterial drugs have made it urgent to develop research to identify new bioactives antibacterial compounds. Jatropha mollissima is a plant endemic to the Caatinga biome, Brazil and this species has antioxidant, antibacterial and antiproliferative action. The present study aimed to evaluate the antibacterial and modulatory potentials of J. mollissima against multiresistant bacterial strains. The phytochemical profile was obtained from gas chromatography coupled to mass spectrometry. J. mollissima presented moderate antibacterial activity and modulated the activity of the antibiotic Norfloxacin, promoting an antagonistic relationship. This was the first study of this nature carried out with J. mollissima.
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Title: Phytochemical analysis, antibacterial activity and antibiotic modifying action of Jatropha mollissima (Pohl.) Baill. (Euphorbiaceae)
Description:
La aparición de cepas bacterianas resistentes y los efectos secundarios de sus fármacos disponibles han hecho investigar nuevos compuestos antibacterianos bioactivos.
Jatropha mollissima es una planta endémica del bioma Caatinga, Brasil.
Existen informes en la literatura de que esta especie tiene acción antioxidante, antibacteriana y antiproliferativa.
El presente estudio tuvo como objetivo evaluar el potencial antibacteriano y modulador de J.
mollissima contra cepas bacterianas multirresistentes.
El perfil fitoquímico se obtuvo por cromatografía de gases junto con espectrometría de masas.
J.
mollissima mostró actividad antibacteriana moderada y moduló la actividad del antibiótico Norfloxacino, promoviendo una relación antagonista.
Este fue el primer estudio de este tipo realizado con J.
mollissima.
The emergence of resistant bacterial strains and the significant increase in side effects of currently available antibacterial drugs have made it urgent to develop research to identify new bioactives antibacterial compounds.
Jatropha mollissima is a plant endemic to the Caatinga biome, Brazil and this species has antioxidant, antibacterial and antiproliferative action.
The present study aimed to evaluate the antibacterial and modulatory potentials of J.
mollissima against multiresistant bacterial strains.
The phytochemical profile was obtained from gas chromatography coupled to mass spectrometry.
J.
mollissima presented moderate antibacterial activity and modulated the activity of the antibiotic Norfloxacin, promoting an antagonistic relationship.
This was the first study of this nature carried out with J.
mollissima.
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