Evaluation of the Ion release from nanoparticles coated orthodontic brackets - In vitro Study

AIM : To evaluate the release of zinc and copper ions from zinc oxide and copper oxide nanoparticles coated orthodontic brackets in artificial saliva under Invitro condition. METHODOLOGY : Thirty six metal brackets were coated with copper oxide (group A) and zinc oxide (group B ) nanoparticles using spray pyrolysis method  and bracket was randomly selected  and assessed under scanning electron microscope. The nano-coated brackets with copper oxide and zinc oxide nanoparticles (Group A and B) were bonded on the extracted first premolar tooth with standard protocol and immersed in artificial saliva at pH of 6.5.  The nanocoated brackets were analysed for ion release using atomic absorption spectrometer  at four different time intervals baseline, day 7, day 14, and day 21 under invitro condition. RESULT  : The highest concentration of zinc ion released from the zinc oxide and copper oxide  nano coated brackets in the artificial saliva was on the 7th day and the quantity of zinc ion released was well below the levels that are toxic to humans throughout the study period. CONCLUSION:  The concentration of zinc ions released zinc oxide nano coated brackets was significantly greater than the concentration of copper ion released from the copper oxide nano-coated brackets in the artificial saliva under similar experimental conditions.