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Green Synthesis of Antibacterial Silver Nanoparticles against Drug Resistant Bacteria
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Background:
Nanotechnology brings a massive revolution in the domain of medical
biotechnology. Plants possess thousands of antimicrobial compounds; these compounds can be extracted
and utilized in the production of medicines.
Objective:
The aim of this research is to design an economical method for the formation of nanoparticles
from plants and explore their antibacterial activity.
Methods:
In the present study, we used the plants Aloe barbadensis, Azadirachta indica, Carica papaya,
Mentha arvensis and Catharanthus roseus. Ethanolic, methanolic and aqueous extracts of the
above mentioned plants were used to prepare silver nanoparticles. Antimicrobial activities of the
nanoparticles of extracts were determined against pathogenic strains of bacteria.
Results:
Results showed that silver nanoparticles are formed from the ethanolic and methanolic extracts
of Azadirachta indica, Carica papaya, Mentha arvensis and Catharanthus roseus and from
the aqueous extracts of Aloe barbadensis and Mentha arvensis. It was observed that nanonoparticles
of ethanolic extracts of Azadirachta indica, Carica papaya, Mentha arvensis and Catharanthus
roseus exhibited the highest antibacterial activity against Pseudomonas specie, E.coli, Pseudomonas
specie and S.typhi, respectively. On the other hand, the nanoparticles of methanolic extracts
of Carica papaya, Mentha arvensis and Catharanthus roseus showed the highest inhibition against
E.coli, whereas, maximum zone of inhibition of Pseudomonas was observed by the action of
methanolic extract of Azadirachta indica. It is also found that nanoparticles of the aqueous extracts
of Aloe barbadensis and Mentha arvensis inhibited the pathogenic strains and showed maximum
activity against Pseudomonas and E.coli, respectively.
Conclusion:
The above results indicate that the nanoparticles formed from the extracts of the tested
plants have high antimicrobial potential and could be utilized in the preparation of medicines to
treat various disorders.
Bentham Science Publishers Ltd.
Title: Green Synthesis of Antibacterial Silver Nanoparticles against Drug Resistant Bacteria
Description:
Background:
Nanotechnology brings a massive revolution in the domain of medical
biotechnology.
Plants possess thousands of antimicrobial compounds; these compounds can be extracted
and utilized in the production of medicines.
Objective:
The aim of this research is to design an economical method for the formation of nanoparticles
from plants and explore their antibacterial activity.
Methods:
In the present study, we used the plants Aloe barbadensis, Azadirachta indica, Carica papaya,
Mentha arvensis and Catharanthus roseus.
Ethanolic, methanolic and aqueous extracts of the
above mentioned plants were used to prepare silver nanoparticles.
Antimicrobial activities of the
nanoparticles of extracts were determined against pathogenic strains of bacteria.
Results:
Results showed that silver nanoparticles are formed from the ethanolic and methanolic extracts
of Azadirachta indica, Carica papaya, Mentha arvensis and Catharanthus roseus and from
the aqueous extracts of Aloe barbadensis and Mentha arvensis.
It was observed that nanonoparticles
of ethanolic extracts of Azadirachta indica, Carica papaya, Mentha arvensis and Catharanthus
roseus exhibited the highest antibacterial activity against Pseudomonas specie, E.
coli, Pseudomonas
specie and S.
typhi, respectively.
On the other hand, the nanoparticles of methanolic extracts
of Carica papaya, Mentha arvensis and Catharanthus roseus showed the highest inhibition against
E.
coli, whereas, maximum zone of inhibition of Pseudomonas was observed by the action of
methanolic extract of Azadirachta indica.
It is also found that nanoparticles of the aqueous extracts
of Aloe barbadensis and Mentha arvensis inhibited the pathogenic strains and showed maximum
activity against Pseudomonas and E.
coli, respectively.
Conclusion:
The above results indicate that the nanoparticles formed from the extracts of the tested
plants have high antimicrobial potential and could be utilized in the preparation of medicines to
treat various disorders.
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