Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Effect of Okra Fruit (Abelmoschus esculentus) Extract on Granzyme Expression and Tumor Mass Diameter of Adenocarcinoma Mammae: An In Vivo Study
View through CrossRef
Background: Breast cancer is currently one of the most common types of cancer suffered by women, with the highest prevalence in all countries in the world. Herbal plants are thought to increase the immune system against tumors, one of which is okra (Abelmoschus esculentus) has the potential as an anti-tumor and anti-carcinogenic. This study aimed to assess the efficacy of ethanol okra extract on granzyme expression and tumor mass diameter in mammary adenocarcinoma of rats treated with adriamycin-cyclophosphamide chemotherapy.
Methods: This study is an experimental study using 28 Sprague Dawley Rats. Data analysis was performed with SPSS version 21 to assess differences in granzyme expression and tumor size.
Results: The combination of chemotherapy and okra fruit extract (P3) showed optimal potential in increasing granzyme expression and reducing mammary tumor size.
Conclusion: The okra fruit extract has potential in the treatment of mammary carcinoma by increasing the expression of granzymes so as to reduce the size of breast carcinoma tumors in vivo.
Title: Effect of Okra Fruit (Abelmoschus esculentus) Extract on Granzyme Expression and Tumor Mass Diameter of Adenocarcinoma Mammae: An In Vivo Study
Description:
Background: Breast cancer is currently one of the most common types of cancer suffered by women, with the highest prevalence in all countries in the world.
Herbal plants are thought to increase the immune system against tumors, one of which is okra (Abelmoschus esculentus) has the potential as an anti-tumor and anti-carcinogenic.
This study aimed to assess the efficacy of ethanol okra extract on granzyme expression and tumor mass diameter in mammary adenocarcinoma of rats treated with adriamycin-cyclophosphamide chemotherapy.
Methods: This study is an experimental study using 28 Sprague Dawley Rats.
Data analysis was performed with SPSS version 21 to assess differences in granzyme expression and tumor size.
Results: The combination of chemotherapy and okra fruit extract (P3) showed optimal potential in increasing granzyme expression and reducing mammary tumor size.
Conclusion: The okra fruit extract has potential in the treatment of mammary carcinoma by increasing the expression of granzymes so as to reduce the size of breast carcinoma tumors in vivo.
Related Results
Complex Collision Tumors: A Systematic Review
Complex Collision Tumors: A Systematic Review
Abstract
Introduction: A collision tumor consists of two distinct neoplastic components located within the same organ, separated by stromal tissue, without histological intermixing...
Abelmoschus esculentus (Okra) leaf modulates some iron profile and inflammatory parameters in Sprague Dawley rats
Abelmoschus esculentus (Okra) leaf modulates some iron profile and inflammatory parameters in Sprague Dawley rats
Abstract
Background
Okra is a multipurpose plant which can be consumed freshly or dried. Okra contains iron, β-carotene and other phenolic compounds with important biologi...
Pembuatan Water Kefir dengan Memanfaatkan Madu dan Okra (Abelmoschus esculentus)
Pembuatan Water Kefir dengan Memanfaatkan Madu dan Okra (Abelmoschus esculentus)
Abstract—Okra is one of vegetable that rarely used by Indonesian people, whereas it is healthty because of its high antioxidant and fiber content. Water kefir is a fermented produc...
PENGARUH TINDAKAN CHEMOTERAPHY TERHADAP PENINGKATAN HARAPAN HIDUP PASIEN CANCER MAMAE DI RSU IMELDA MEDAN PEKERJA INDONESIA
PENGARUH TINDAKAN CHEMOTERAPHY TERHADAP PENINGKATAN HARAPAN HIDUP PASIEN CANCER MAMAE DI RSU IMELDA MEDAN PEKERJA INDONESIA
ABSTRAK
Carcinoma mammae (ca mammae) adalah sebuah tumor ganas yang tumbuh dalam jaringan mammae, yang diduga berpengaruh pada kualitas hidup penderitanya. Pengaruh k...
Effect of Okra Fruit (Abelmoschus esculentus) Extract on Adenocarcinoma Mammae by Assessing Caspase-3 Expression and Apoptosis Index: An In Vivo Study
Effect of Okra Fruit (Abelmoschus esculentus) Extract on Adenocarcinoma Mammae by Assessing Caspase-3 Expression and Apoptosis Index: An In Vivo Study
Background: Breast cancer is cancer in women with the highest incidence. Adriamycin-cyclophosphamide (AC) chemotherapy is a breast cancer therapy with good efficacy, but its effect...
British Food Journal Volume 35 Issue 5 1933
British Food Journal Volume 35 Issue 5 1933
The Fruit Control Act, 1924, is an important one as it provides for the establishment of a Fruit Control Board, and is described as an “Act to make Provision for Control of the Fru...
Optimum Plant Density of Okra and Intercropping Effects on Yields of Egusi Melon-Okra Mixture, at Makurdi, Nigeria
Optimum Plant Density of Okra and Intercropping Effects on Yields of Egusi Melon-Okra Mixture, at Makurdi, Nigeria
A field experiment was conducted from August to November, during the 2012 and 2013 cropping seasons at the Research Farm, University of Agriculture, Makurdi, Nigeria, to identify t...
The Effectivity of Supplementation Artemisia vulgaris for Adenocarcinoma Mammae Chemotherapy to Reduce CD 34 and Tumor Massa Diameter (Study in C3H Mice Given Adriamycin - Cyclophosphamide Chemotherapy)
The Effectivity of Supplementation Artemisia vulgaris for Adenocarcinoma Mammae Chemotherapy to Reduce CD 34 and Tumor Massa Diameter (Study in C3H Mice Given Adriamycin - Cyclophosphamide Chemotherapy)
Introduction: Breast cancer is still a major health problem in the world. In the case of breast cancer, surgery is the main treatment option besides chemotherapy, radiation, and im...