The Effects of Powerlifting-Based Training on Hormonal, Metabolic and Lipid Profile Parameters in Athletes: A Randomized Controlled Trial

Abstract Objective: This study investigated the effects of a powerlifting-based training program on hormonal, metabolic and lipid profile parameters in male basketball players. Methods: This randomized controlled experimental study was conducted according to CONSORT guidelines. Thirty male basketball players aged 18–24 years were included in the study and randomly assigned to an exercise group (EG, n = 15) and a control group (CG, n = 15). Both groups continued routine basketball training three days a week for six weeks. In addition, the EG group underwent a powerlifting-based training program. Thyroid hormones (TSH, T3, and T4), insulin, glucose, growth hormone, testosterone, and blood lipid profile parameters were measured before and after the intervention. Data were analyzed using two-way repeated measures analysis of variance. Results: Significant increases in TSH, T3, T4, insulin, growth hormone, and testosterone levels were observed in the exercise group after the intervention (p<0.001). In contrast, significant decreases were observed in glucose, total cholesterol, LDL, and triglyceride levels, while a significant increase was observed in HDL levels. No significant changes were found in the parameters measured in the control group. Moderate to high effect sizes were determined for most variables. Conclusion: Powerlifting-based training programs positively influence the hormonal balance and biochemical profile of male basketball players. These findings demonstrate that powerlifting-based strength training is an effective and feasible complementary training method for basketball players.