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Substrate-derived Sortase A inhibitors: targeting an essential virulence factor of Gram-positive pathogenic bacteria
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A series of peptidomimetic Sortase A inhibitors is reported. These compounds show inhibition activity of the Sortase A enzyme and efficiently prevent biofilm formation of S. aureus.
Royal Society of Chemistry (RSC)
Title: Substrate-derived Sortase A inhibitors: targeting an essential virulence factor of Gram-positive pathogenic bacteria
Description:
A series of peptidomimetic Sortase A inhibitors is reported.
These compounds show inhibition activity of the Sortase A enzyme and efficiently prevent biofilm formation of S.
aureus.
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