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Assessment of Disease Activity in Small Bowel Crohn’s Disease: Comparison between Endoscopy and Magnetic Resonance Enterography Using MRIA and Modified MRIA Score

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Objectives. To retrospectively compare the results of the MRIA (magnetic resonance index of activity) with a modified MRIA (mMRIA), which was calculated excluding from MRIA formula the data of relative contrast enhancement (RCE).Materials and Methods. MR-E and corresponding endoscopic records of 100 patients were reviewed. MRIA, mMRIA, and SES endoscopic index were calculated for all the patients. Namely, MRIA was calculated as follows: (1.5 × wall thickening + 0.02 × RCE + 5 × intramural edema + 10 × ulcers), while mMRIA was calculated with the modified formula (1.5 × wall thickening + 5 × intramural edema + 10 × ulcers).Results. Mean MRIA and mMRIA values were 19.3 and 17.68, respectivelyp<0.0001. A significant correlationp<0.0001was observed between MRIA and mMRIA scores and between both MR indexes and SESp<0.0001.Conclusions. mMRIA was comparable to MRIA in the evaluation of disease activity in Crohn’s disease.
Title: Assessment of Disease Activity in Small Bowel Crohn’s Disease: Comparison between Endoscopy and Magnetic Resonance Enterography Using MRIA and Modified MRIA Score
Description:
Objectives.
To retrospectively compare the results of the MRIA (magnetic resonance index of activity) with a modified MRIA (mMRIA), which was calculated excluding from MRIA formula the data of relative contrast enhancement (RCE).
Materials and Methods.
MR-E and corresponding endoscopic records of 100 patients were reviewed.
MRIA, mMRIA, and SES endoscopic index were calculated for all the patients.
Namely, MRIA was calculated as follows: (1.
5 × wall thickening + 0.
02 × RCE + 5 × intramural edema + 10 × ulcers), while mMRIA was calculated with the modified formula (1.
5 × wall thickening + 5 × intramural edema + 10 × ulcers).
Results.
Mean MRIA and mMRIA values were 19.
3 and 17.
68, respectivelyp<0.
0001.
A significant correlationp<0.
0001was observed between MRIA and mMRIA scores and between both MR indexes and SESp<0.
0001.
Conclusions.
mMRIA was comparable to MRIA in the evaluation of disease activity in Crohn’s disease.

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