Profil Biokimia Darah Kuda yang Terlacak Berpenyakit Surra di Sumba Timur, Nusa Tenggara Timur, Indonesia

The infectious animal disease known as surra, or trypanosomiasis in animals, is caused by Trypanosoma evansi.In Indonesia, surra has been recognized as a strategic infectious disease affecting animals. East Nusa Tenggara Province, identified as a center of livestock farming in Indonesia, is also known as an endemic area for surra and requires attention. Therefore, this study was aimed to determine the biochemical profile of blood in horses infected with T. evansi in East Sumba Regency. The parameters observed included blood glucose levels, total protein, creatinine, alanine transaminase (ALT), and aspartate transaminase (AST). Samples were collected from horses raised by the community in East Sumba Regency. The biochemicalexamination was performed using the Photometer 5010V5+ instrument.Blood glucose was examined usingGOD-PAP deproteinization method; totalprotein was determined using a photometry colorimetric test; creatinine was carried using the Jaffe-fixed time kinetic method; ALT and AST were performed using the kinetic method; and UV Test. The results showed that the average biochemical profile of blood in Sumba horses infected with T. evansi was glucose (68.17±5.11mg/dL); protein (5.417±1.82g/dL); creatinine (1.74±0.39mg/dL); urea (28.93±6.26mg/dL); AST (357.00±117.02U/L); and ALT (20.17±6.30U/L). Meanwhile, the average blood biochemical profile in Sumba horses not infected with T. evansi was glucose (99.00±14.96mg/dL); protein (7.20±1.72g/dL); creatinine (1.55±0.51mg/dL);urea (28.13±6.88mg/dL); AST (312.83±94.42U/L); and ALT (23.33±9.45U/L). Blood glucose levels in horsesinfected with T. evansiwere significantly lower (P<0.01) compared to non-infected horses. Apart from blood glucose levels, all observed parameters were in normal ranges.