ETIOPATHOLOGICAL STUDY OF VIKRITA KLEDA WITH SPECIAL REFER-ENCE TO LABORATORY PARAMETERS

This study, “Etiopathological Study of Vikrita Kleda with Special Reference to Laboratory Parameters,” explores the role of Kleda as an etiopathological factor in selected disorders and its correlations with modern investigations. In Ayurveda, Kleda refers to the body’s fluid-moisture component, whose pathological state—Vikrita Kleda—contributes to the development of disease. To examine its clinical relevance, 100 patients (20 each of Prameha, Sthoulya, Shotha, Kustha, and Vrana) were studied. Manifestations included Sarvanga-gata, Dhatu-gata, and disease-specific forms. Results showed Sarvanga-gata Kleda predominated in Prameha (90%), Dhatu-gata Kleda in Sthoulya (85%) and Prameha (80%), while Sothagata, Kusthagata, and Vranagata Kleda were strongly disease-specific. Ama was frequent in Vrana (95%) and Shotha (80%), suggesting its role in chronic inflammation. Laboratory correlations revealed that fasting and postprandial glucose levels were key indicators for Prameha-gata Kleda. At the same time, ESR and CRP were key indicators for Sarvanga-gata and Dhatu-gata Kleda, respectively. Additionally, serum cholesterol levels were a key indicator for Sthoulya. Urine examination effectively assessed Mutraja Kleda, while leukocyte counts showed no significance. The study con-firms the clinical relevance of Kleda and establishes measurable correlations with contemporary parameters, lay-ing the groundwork for standardised diagnostic tools and interdisciplinary research.