Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Wagner‐Meerwein rearrangement of a [3.3.3]‐ to a [4.3.3]propellane: deuterium tracer and conformational analysis
View through CrossRef
AbstractFormation of (−)‐[4.3.3]propellane 4 from (−)‐14‐hydroxymodhephene (2) proceeds through a Wagner‐Meerwein rearrangement via C3C4 bond‐shift to give a stable intermediate, dimethylcyclohexadienyl cation A, which undergoes deprotonation. Herein, this mechanism was investigated by using a deuterium labeled substrate at the C‐14 methylene group of (−)‐2, which was incorporated into the C‐4 position of (−)‐[4.3.3]propellane 4. The stereostructure of (−)‐4 was investigated by applying a combination of NMR experimental and theoretical approaches. Copyright © 2007 John Wiley & Sons, Ltd.
Title: Wagner‐Meerwein rearrangement of a [3.3.3]‐ to a [4.3.3]propellane: deuterium tracer and conformational analysis
Description:
AbstractFormation of (−)‐[4.
3.
3]propellane 4 from (−)‐14‐hydroxymodhephene (2) proceeds through a Wagner‐Meerwein rearrangement via C3C4 bond‐shift to give a stable intermediate, dimethylcyclohexadienyl cation A, which undergoes deprotonation.
Herein, this mechanism was investigated by using a deuterium labeled substrate at the C‐14 methylene group of (−)‐2, which was incorporated into the C‐4 position of (−)‐[4.
3.
3]propellane 4.
The stereostructure of (−)‐4 was investigated by applying a combination of NMR experimental and theoretical approaches.
Copyright © 2007 John Wiley & Sons, Ltd.
Related Results
Wagner‐Meerwein Rearrangement
Wagner‐Meerwein Rearrangement
AbstractThe class of 1,2‐rearrangement of carbocation intermediates, from which the migratory group rearranges from an adjacent carbon atom to the carbocation center to form a more...
Diffusion and Ion Conduction in Cation-Conducting Oxide Glasses
Diffusion and Ion Conduction in Cation-Conducting Oxide Glasses
In this Chapter we review knowledge about diffusion and cation conduction in oxide glasses. We first remind the reader in Section 1 of major aspects of the glassy state and recall ...
Studies on the near-surface trapping of deuterium in implantation experiments
Studies on the near-surface trapping of deuterium in implantation experiments
Abstract
Surface-shifted deuterium profiles are re-examined in deuterium-ion irradiation experiments by using a combined experimental and modelling approach. Recryst...
A Study of the Hydrogen Uptake Mechanism in Zirconium Alloys
A Study of the Hydrogen Uptake Mechanism in Zirconium Alloys
Hydrogen uptake in zirconium alloy CANDU (CANada Deuterium Uranium) pressure tubes and other core components is controlled by the rate of transport of atomic/ionic species across t...
Extended Duration of DH–JH Rearrangement in Immunoglobulin Heavy Chain Transgenic Mice: Implications for Regulation of Allelic Exclusion
Extended Duration of DH–JH Rearrangement in Immunoglobulin Heavy Chain Transgenic Mice: Implications for Regulation of Allelic Exclusion
Here we show that suppression of VH–DJH rearrangement in mice bearing a μ heavy (H) chain transgene (μ-tg mice) is associated with an extended period of DH–JH rearrangement, the fi...
EGFR TKI PET/CT in advanced stage non-small cell lung cancer patients
EGFR TKI PET/CT in advanced stage non-small cell lung cancer patients
An overview of biomarker development is provided in chapter 2.PET tracer-based biomarkers can be used to monitor different biological or clinical metrics. A clinically important bi...
Westphalen Rearrangement
Westphalen Rearrangement
AbstractThis rearrangement is an acid‐promoted Wagner–Meerwein rearrangement of 5‐hydroxycholesterol derivatives with a substituent at C‐6 in β‐configuration, from which the 5‐hydr...