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Peripheral Nerve Biopsy
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Nerve biopsy is an important part of the diagnostic armamentarium in the evaluation of a number of diseases, including vasculitis, some hereditary neuropathies, toxic and metabolic neuropathies, inflammatory demyelinating conditions (such as chronic inflammatory demyelinating polyneuropathy), and neoplastic and nonneoplastic infiltrative diseases, such as sarcoidosis, amyloidosis, neurolymphomatosis, and other metastatic tumor infiltration. Options for nerve biopsy include whole-nerve biopsy (e.g., biopsy of the sural nerve, superficial peroneal nerve, or superficial sensory radial nerve) or targeted fascicular biopsy. This chapter identifies indications for nerve biopsy, discusses important considerations for choosing the biopsy target, and explains in detail the surgical procedure for common nerve biopsies.
Title: Peripheral Nerve Biopsy
Description:
Nerve biopsy is an important part of the diagnostic armamentarium in the evaluation of a number of diseases, including vasculitis, some hereditary neuropathies, toxic and metabolic neuropathies, inflammatory demyelinating conditions (such as chronic inflammatory demyelinating polyneuropathy), and neoplastic and nonneoplastic infiltrative diseases, such as sarcoidosis, amyloidosis, neurolymphomatosis, and other metastatic tumor infiltration.
Options for nerve biopsy include whole-nerve biopsy (e.
g.
, biopsy of the sural nerve, superficial peroneal nerve, or superficial sensory radial nerve) or targeted fascicular biopsy.
This chapter identifies indications for nerve biopsy, discusses important considerations for choosing the biopsy target, and explains in detail the surgical procedure for common nerve biopsies.
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