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Atracurium infusion in total intravenous anesthesia
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The neuromuscular blocking effect of atracurium given as a bolus dose (0.5 mg·kg‐1) followed by a maintenance infusion was studied during two different anesthetic techniques. It has been reported that benzodiazepines interact with non‐depolarising neuromuscular blockers. In this study no difference was found in the effect of atracurium given with conventional fentanyl/nitrous oxide anesthesia when compared to total intravenous anesthesia using midazolam/alfentanil. More than 90% twitch depression was achieved after 123 and 137 s, respectively. Recovery time to 10% twitch height following the bolus dose was around 32 min. The dosage range for atracurium given by infusion (0.29‐0.44 mg·kg‐1·‐1) was confirmed.
Title: Atracurium infusion in total intravenous anesthesia
Description:
The neuromuscular blocking effect of atracurium given as a bolus dose (0.
5 mg·kg‐1) followed by a maintenance infusion was studied during two different anesthetic techniques.
It has been reported that benzodiazepines interact with non‐depolarising neuromuscular blockers.
In this study no difference was found in the effect of atracurium given with conventional fentanyl/nitrous oxide anesthesia when compared to total intravenous anesthesia using midazolam/alfentanil.
More than 90% twitch depression was achieved after 123 and 137 s, respectively.
Recovery time to 10% twitch height following the bolus dose was around 32 min.
The dosage range for atracurium given by infusion (0.
29‐0.
44 mg·kg‐1·‐1) was confirmed.
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