Impact of Flax Seed Oil on Caffeinated Energy Drink Induced Osteoporotic Changes in Thickness of Cortical Bone in Adult Male Albino Rats

Objective: To appraise defensive impact of flax seed oil on osteoporotic changes in thickness of cortical bonecaused by caffeinated energy drinks in adult male albino ratsMaterial &Methods: It was an experimental study accomplished at department of Anatomy, Shaikh ZayedPost graduate Medical Institute Lahore, for 8 weeks. 32 adult male albino rats (250-300gm) were equallydivided into four groups by randomization and acclimatized for 1week. Group A (Control) was given corn oil5ml per kg along with basal diet. Group B (Experimental) was given caffeinated energy drink (15ml per kg)along with corn oil. Group C (Experimental) was given caffeinated energy drink (15 ml per kg) and 40% flaxseed oil (5ml per kg), while group D (Experimental )was given caffeinated energy drink (15ml per kg) and60% flax seed oil (5ml per kg) once daily for 8 weeks. The femora were dissected out, observed for grossparameters and right femora were selected for histological examination.Results: Significant difference in mean thickness of cortical bone among experimental groups (p = 0.000)was observed.Conclusion: Flax seed oil helped in alleviating metamorphosis in thickness of cortical bone induced bycaffeinated energy drink.Keywords: Flax seed oil, caffeinated energy drink, thickness of cortical boneHow to cite: Waseem A, Zaheer A, Iqbal S. Qamar H, Shaveer K, Saleem A. Impact of Flax Seed Oil onCaffeinated Energy Drink Induced Osteoporotic Changes in Thickness of Cortical Bone in Adult MaleAlbino Rats. Esculapio - JSIMS 2026;22(01):96-100.DOI: 10.51273/esculap.v22i01.1401