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Clinical course of intoxication with the new anticonvulsant drug perampanel
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ABSTRACTPerampanel has recently been approved as an anticonvulsant drug for focal epilepsies. Phase III trials have shown good tolerability, although data regarding effects of high doses of perampanel are not available. Here, we describe the first case of a 34‐year‐old patient with perampanel intoxication and attempted suicide, in which the recommended daily dose of perampanel was exceeded ten‐fold. Clinical signs of the intoxication and possible psychotropic effects are described.
Title: Clinical course of intoxication with the new anticonvulsant drug perampanel
Description:
ABSTRACTPerampanel has recently been approved as an anticonvulsant drug for focal epilepsies.
Phase III trials have shown good tolerability, although data regarding effects of high doses of perampanel are not available.
Here, we describe the first case of a 34‐year‐old patient with perampanel intoxication and attempted suicide, in which the recommended daily dose of perampanel was exceeded ten‐fold.
Clinical signs of the intoxication and possible psychotropic effects are described.
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Sobering truths: The influence of victim intoxication status and expert testimony on mock jury decision-making
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Objectives: Victims are often intoxicated with alcohol during crimes and jurors must evaluate their testimony at trial. This study investigated the impact of (1) a victim’s intoxic...
Sobering truths: The influence of victim intoxication status and expert testimony on mock jury decision-making
Sobering truths: The influence of victim intoxication status and expert testimony on mock jury decision-making
Objectives: Victims are often intoxicated with alcohol during crimes and jurors must evaluate their testimony at trial. This study investigated the impact of (1) a victim’s intoxic...