Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Pathophysiology of uterine leiomyomas
View through CrossRef
Uterine leiomyomas is the most common benign neoplasia in women, one of the most frequent causes of infertility in reproductive years, and the leading cause for hysterectomy. The pathophysiology of uterine leiomyomas is uncertain. Therefore, therapeutic approaches have been primarily empirical. It is now well documented that growth factors control the functional and possibly the histological integrity of several tissues. Recently the presence of growth substances in uterine tissues suggested that the role of sex steroid hormones in the pathophysiology of leiomyomas may be mediated by substances influencing the proliferation of smooth muscle cells and fibroblasts. This report summarizes the data related to the pathophysiology of leiomyomas, which indicate a possible role of growth factors in uterine leiomyomas.Key words: leiomyomas, growth factors, uterus, smooth muscle cells, fibroblasts.
Title: Pathophysiology of uterine leiomyomas
Description:
Uterine leiomyomas is the most common benign neoplasia in women, one of the most frequent causes of infertility in reproductive years, and the leading cause for hysterectomy.
The pathophysiology of uterine leiomyomas is uncertain.
Therefore, therapeutic approaches have been primarily empirical.
It is now well documented that growth factors control the functional and possibly the histological integrity of several tissues.
Recently the presence of growth substances in uterine tissues suggested that the role of sex steroid hormones in the pathophysiology of leiomyomas may be mediated by substances influencing the proliferation of smooth muscle cells and fibroblasts.
This report summarizes the data related to the pathophysiology of leiomyomas, which indicate a possible role of growth factors in uterine leiomyomas.
Key words: leiomyomas, growth factors, uterus, smooth muscle cells, fibroblasts.
Related Results
Abstract 1538: Molecular characterization of uterine leiomyomas, histopathological uterine leiomyoma subtypes, and uterine leiomyosarcomas
Abstract 1538: Molecular characterization of uterine leiomyomas, histopathological uterine leiomyoma subtypes, and uterine leiomyosarcomas
Abstract
Uterine leiomyomas (ULMs) are the most common tumors of the female genital tract. They originate from the smooth muscle cells of the myometrium. Despite the...
Assessing Clinicopathologic factors in uterine leiomyoma patients in East Libya.
Assessing Clinicopathologic factors in uterine leiomyoma patients in East Libya.
Introduction: Uterine leiomyomas (ULs) are benign tumors of smooth muscle tissue; occur in women of reproductive age, with clinical manifestations depending on their size, and loca...
An Uncommon Site of Cutaneous Leiomyoma on the Heel of the Foot
An Uncommon Site of Cutaneous Leiomyoma on the Heel of the Foot
Leiomyomas are common benign tumours of smooth muscles, often occurring in the uterine muscle wall. These growths usually appear during a woman’s reproductive years and are not mal...
The Prevalence and Post-Operative Complications of Uterine Leiomyomas in South-Western Nigeria and Northern Nigeria: A Comparative Review
The Prevalence and Post-Operative Complications of Uterine Leiomyomas in South-Western Nigeria and Northern Nigeria: A Comparative Review
Background: Uterine Leiomyoma are benign tumors which commonly affect women of reproductive age, however only a subset of women has their fibroids clinically detected, symptomatic ...
Heart Failure Associated with Giant Uterine Leiomyoma: A Case Report
Heart Failure Associated with Giant Uterine Leiomyoma: A Case Report
Heart failure impairs the heart’s pumping ability and triggers catecholamine production as an adaptive mechanism. Uterine leiomyomas are common tumors of the female reproductive tr...
Liangfang Wenjing decoction regulates endoplasmic reticulum stress-mediated apoptosis to alleviate uterine microvascular injury in cold-stressed rats
Liangfang Wenjing decoction regulates endoplasmic reticulum stress-mediated apoptosis to alleviate uterine microvascular injury in cold-stressed rats
BackgroundCold exposure can induce microvascular damage, which in turn contributes to various gynecological disorders. Liangfang Wenjing Decoction (LFWJD), a classical botanical dr...
Integrative transcriptomics analysis for uterine leiomyosarcoma identifies aberrant activation of cell cycle-dependent kinases and their potential therapeutic significance
Integrative transcriptomics analysis for uterine leiomyosarcoma identifies aberrant activation of cell cycle-dependent kinases and their potential therapeutic significance
Abstract
Purpose
Uterine leiomyosarcoma is among the most aggressive gynecological malignancies. No effective treatment strateg...
Risk of Uterine Rupture and Dehiscence Among Women Attempting a Vaginal Birth After a Low Vertical Uterine Incision [A232]
Risk of Uterine Rupture and Dehiscence Among Women Attempting a Vaginal Birth After a Low Vertical Uterine Incision [A232]
INTRODUCTION:
The risk of uterine rupture after a prior low vertical (LVCS) is unknown. The objective of this study was to estimate the risk of uterine rupture in indiv...