TUNING AND VALIDATION OF THE NEW RADCALC 3D MONTE CARLO BASED PRE-TREATMENT PLAN VERIFICATION TOOL

Verification procedures for patient-specific quality assurance (QA) in advanced radiotherapy are laborious and time-consuming. Moreover, it has been shown that these procedures cannot detect some inaccuracies for some particular complex cases due to tissue inhomogeneity and highly modulated plans. Secondary dose calculation verification of radiotherapy plans is an important aspect in patient-specific QA. A suitably optimized software, RadCalc equipped with 3D Monte Carlo Module (MC), was used to dosimetrically verify radiotherapy treatment plans where the measured dose distributions can be inaccurate due to the TPS dose calculation algorithm and/or treatment unit delivery uncertainties. MC Models were built using specific commissioning measurements and then the Additional Radiation to Light Field Offset parameter (Dosimetric Leaf Gap parameter) was tuned to achieve the best dose comparison agreement with phantom patient-specific QA measurements. The results showed a good agreement between the TPS and the simulations. RadCalc MC also allows to better estimate the plan doses in lung cancer patients and to detect the presence of possible inaccuracies due to tissue inhomogeneity, which is not estimable with a homogeneous phantoms.