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Gout research tools
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Although most tools used in gout research are generic, there are some important gout-specific instruments. New gout classification criteria were published in 2015. Outcome measure domains have been identified for both acute and chronic gout studies. A preliminary flare definition has been reported. Gout-specific, patient-reported outcome measure instruments allow assessment of gout disease activity and impact of tophi. Imaging scoring systems allow quantification of joint damage, inflammation, and urate burden in gout.
Title: Gout research tools
Description:
Although most tools used in gout research are generic, there are some important gout-specific instruments.
New gout classification criteria were published in 2015.
Outcome measure domains have been identified for both acute and chronic gout studies.
A preliminary flare definition has been reported.
Gout-specific, patient-reported outcome measure instruments allow assessment of gout disease activity and impact of tophi.
Imaging scoring systems allow quantification of joint damage, inflammation, and urate burden in gout.
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Introduction to gout
Gout is a chronic condition of monosodium urate crystal deposition. It is the most common form of inflammatory arthritis in adults, and leads to recurrent flares of severe joint da...
Pathophysiology of gout
Pathophysiology of gout
The clinical features of gout occur in response to monosodium urate (MSU) crystals. Gout should be considered a chronic disease of MSU crystal deposition. A number of pathophysiolo...
Epidemiology of gout
Epidemiology of gout
Gout is the most prevalent inflammatory arthritis in men. Data from epidemiological studies conducted in several countries suggest that the prevalence and incidence of gout have ri...
Imaging in gout
Imaging in gout
Identification of monosodium urate (MSU) crystals is the gold standard for gout diagnosis. Serum urate is an important test for both gout diagnosis and effective management. For al...
Principles of gout management
Principles of gout management
The main goal of therapy is to achieve ‘remission’—the absence of gout attacks and tophi. A sustained reduction in serum urate is critical to the long-term management of gout and w...
Aetiopathogenesis
Aetiopathogenesis
Gout is a common and treatable cause of musculoskeletal disability. There have been major advances in scientific understanding and treatment of gout in the last decade. Despite the...
Clinical features of gout
Clinical features of gout
About 60% of the variance in serum urate levels can be explained by inherited genetic factors, but the extent of the contribution of genetic factors to gout in the presence of hype...

