Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Copper-Promoted Cross-Coupling Reactions for the Synthesis of Aryl(difluoromethyl)phosphonates Using Trimethylsilyl(difluoromethyl)phosphonate
View through CrossRef
A convenient and effective route for the synthesis of aryl(difluoromethyl)phosphonates has been developed based on cross-coupling reactions. Upon treatment with a stoichiometric amount (or a catalytic amount in some cases) of CuI and CsF, aryl iodides reacted smoothly with (silyldifluoromethyl)phosphonates to give the corresponding aryl(difluoromethyl)phosphonates in good yields.
Title: Copper-Promoted Cross-Coupling Reactions for the Synthesis of Aryl(difluoromethyl)phosphonates Using Trimethylsilyl(difluoromethyl)phosphonate
Description:
A convenient and effective route for the synthesis of aryl(difluoromethyl)phosphonates has been developed based on cross-coupling reactions.
Upon treatment with a stoichiometric amount (or a catalytic amount in some cases) of CuI and CsF, aryl iodides reacted smoothly with (silyldifluoromethyl)phosphonates to give the corresponding aryl(difluoromethyl)phosphonates in good yields.
Related Results
Synthesis of phosphoantigens and chiral trisphosphonates
Synthesis of phosphoantigens and chiral trisphosphonates
<p>Phosphorus is an element that is essential for life, and is used in the synthesis of many proteins, carbohydrates and deoxyribonucleic acids. Phosphorus often exists in th...
Suzuki Coupling
Suzuki Coupling
Abstract
This reaction is a palladium‐catalyzed cross‐coupling between an aryl or vinyl halide (or its equivalents and
pseudo‐
halide...
Stability and Efficiency of Mixed Aryl Phosphonate Prodrugs
Stability and Efficiency of Mixed Aryl Phosphonate Prodrugs
AbstractA set of phosphonate prodrugs of a butyrophilin ligand was synthesized and evaluated for plasma stability and cellular activity. The mixed aryl acyloxy esters were prepared...
Mononuclear Palladium(I) Aryl Complexes Performs Cross-Coupling Reactions with Organic Halides
Mononuclear Palladium(I) Aryl Complexes Performs Cross-Coupling Reactions with Organic Halides
Mononuclear Pd(I) species represent the least understood Pd intermediates in Pd-catalyzed reactions and isolable complexes of the type are exceedingly rare. Herein, we report the s...
Nickel-Catalyzed Cross-Electrophile Coupling Reactions of Alcohols and Their Derivatives
Nickel-Catalyzed Cross-Electrophile Coupling Reactions of Alcohols and Their Derivatives
AbstractNickel-catalyzed cross-electrophile coupling of halide coupling partners has emerged as a powerful tool for constructing C–C bonds under mild conditions. However, the limit...
Ullmann Coupling
Ullmann Coupling
Abstract
This reaction is a copper‐promoted reductive coupling between aryl halides to form biaryls and is generally referred to as the Ullmann coupling. The study finds ...
The interaction between neural populations: Additive versus diffusive coupling
The interaction between neural populations: Additive versus diffusive coupling
AbstractModels of networks of populations of neurons commonly assume that the interactions between neural populations are via additive or diffusive coupling. When using the additiv...
CRYSTAL STRUCTURES OF TWO PHOSPHONATE SALTS: MONOCYCLOHEXYLAMMONIUM HYDROGEN PHOSPHONATE AND MONOCYCLOHEXYLAMMONIUM PHENYL PHOSPHONATE
CRYSTAL STRUCTURES OF TWO PHOSPHONATE SALTS: MONOCYCLOHEXYLAMMONIUM HYDROGEN PHOSPHONATE AND MONOCYCLOHEXYLAMMONIUM PHENYL PHOSPHONATE
Hydrogen phosphonate anions and monocyclohexylammonium cations interacting through hydrogen bonds conduct to the formation of a salt namely monocyclohexylammonium hydrogen phosphon...