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CREPE: A Shiny App for Transcription Factor Cataloguing
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Abstract
Transcription factors (TFs) are proteins that directly interpret the genome to regulate gene expression and determine cellular phenotypes. TF identification is a common first step in unravelling gene regulatory networks. We present CREPE, an R Shiny app to catalogue and annotate TFs. CREPE was benchmarked against curated human transcription factor datasets. Next, we use CREPE to explore the TF repertoires of
Heliconius erato and Heliconius melpomene
butterflies. CREPE is available as a Shiny app package available at GitHub (
github.com/dirostri/CREPE
).
Title: CREPE: A Shiny App for Transcription Factor Cataloguing
Description:
Abstract
Transcription factors (TFs) are proteins that directly interpret the genome to regulate gene expression and determine cellular phenotypes.
TF identification is a common first step in unravelling gene regulatory networks.
We present CREPE, an R Shiny app to catalogue and annotate TFs.
CREPE was benchmarked against curated human transcription factor datasets.
Next, we use CREPE to explore the TF repertoires of
Heliconius erato and Heliconius melpomene
butterflies.
CREPE is available as a Shiny app package available at GitHub (
github.
com/dirostri/CREPE
).
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