Search engine for discovering works of Art, research articles, and books related to Art and Culture
ShareThis
Javascript must be enabled to continue!

Compaction behaviour and mechanical characteristics of chewable binary tablet mixture containing lactose (Flowlac 100) and date (Phoenix dactylifera) powders

View through CrossRef
This study aimed to develop a formulation for a chewable tablet using date powder (DP) and Flowlac 100 utilizing a direct compression method. The powders were compacted as single and binary mixtures at five different formulations (DPL1, DPL2, DPL3, DPL4 and DPL5) to study their compaction behaviour. Stressor ranging from 15 to 74 MPa in a cylindrical die with flat face punches were introduced during the fabrication process, and the mechanical properties (plastic work, flexible work and tensile strength) of formed tablets were investigated. Findings of this study demonstrated that with a high percentage of DP in the formulation resulted in a high reading of plastic work, while a low amount of DP revealed low elastic work. Tensile strength of the tablet, on the other hand, varies with the percentage of DP present and applied pressure used. Formulation with 60% DP (DPL4) displayed the highest tensile strength compared to the other formulations, and it is coherent with industrial preferable tensile strength limit. In conclusion, the current findings could be useful in formulation and fabricating date chewable tablet which can be used as a food supplement by all categories of consumers since it is easy to be consumed by a wide range of age.
Title: Compaction behaviour and mechanical characteristics of chewable binary tablet mixture containing lactose (Flowlac 100) and date (Phoenix dactylifera) powders
Description:
This study aimed to develop a formulation for a chewable tablet using date powder (DP) and Flowlac 100 utilizing a direct compression method.
The powders were compacted as single and binary mixtures at five different formulations (DPL1, DPL2, DPL3, DPL4 and DPL5) to study their compaction behaviour.
Stressor ranging from 15 to 74 MPa in a cylindrical die with flat face punches were introduced during the fabrication process, and the mechanical properties (plastic work, flexible work and tensile strength) of formed tablets were investigated.
Findings of this study demonstrated that with a high percentage of DP in the formulation resulted in a high reading of plastic work, while a low amount of DP revealed low elastic work.
Tensile strength of the tablet, on the other hand, varies with the percentage of DP present and applied pressure used.
Formulation with 60% DP (DPL4) displayed the highest tensile strength compared to the other formulations, and it is coherent with industrial preferable tensile strength limit.
In conclusion, the current findings could be useful in formulation and fabricating date chewable tablet which can be used as a food supplement by all categories of consumers since it is easy to be consumed by a wide range of age.

Related Results

Evolution of Antimicrobial Resistance in Community vs. Hospital-Acquired Infections
Evolution of Antimicrobial Resistance in Community vs. Hospital-Acquired Infections
Abstract Introduction Hospitals are high-risk environments for infections. Despite the global recognition of these pathogens, few studies compare microorganisms from community-acqu...
Perbandingan Beberapa Bahan Pengisi pada Formulasi Tablet Hisap
Perbandingan Beberapa Bahan Pengisi pada Formulasi Tablet Hisap
Abstrak. Tablet hisap adalah tablet padat yang mengandung satu atau lebih bahan obat. Biasanya tablet hisap ini memiliki rasa dan aroma yang manis sehingga dapat larut perlahan dal...
Formulation development of chewable tablets containing Phyllanthus emblica Linn. fruit extract by direct compression
Formulation development of chewable tablets containing Phyllanthus emblica Linn. fruit extract by direct compression
Indian gooseberry (Phyllanthus emblica Linn.), a plant in family Euphobiaceae, is a tree growing in tropical parts of Southeast Asia. Its fruits have been widely used in folk medic...
Systematic review: Diagnosis, treatment and management strategies of lactose intolerance
Systematic review: Diagnosis, treatment and management strategies of lactose intolerance
Lactose, a disaccharide composed of glucose and galactose, plays a pivotal role in the nutritional physiology of mammals, particularly during infancy. This thesis explores the comp...
Determination Of Nutrients And Anti-nutrients Contents Of Phoenix Dactylifera
Determination Of Nutrients And Anti-nutrients Contents Of Phoenix Dactylifera
Background: Date palms (Phoenix dactylifera) are considered a complete diet and an important item of food. It is a common fruit in Nigeria with both nutritional and anti-nutritiona...
Lactose digestion in pregnant African-Americans
Lactose digestion in pregnant African-Americans
AbstractObjective:This paper reports on the status of lactose digestion during early and late pregnancy and at 8 weeks postpartum in an African-American population. The hypothesis ...
REVIEW ARTIKEL: PENGARUH PENAMBAHAN KONSENTRASI MALTODEXTRIN TERHADAP KARAKTERISTIK FISIK SEDIAAN TABLET
REVIEW ARTIKEL: PENGARUH PENAMBAHAN KONSENTRASI MALTODEXTRIN TERHADAP KARAKTERISTIK FISIK SEDIAAN TABLET
Sediaan Tablet merupakan sediaan paling dikenal sebagai sediaan takaran tunggal yang dikempa cetak sehingga padat dan berbentuk tabung pipih atau sirkuler dengan permukaan rata ata...
Review Jurnal: Evaluasi Kekerasan Sediaan Tablet Kunyah dengan Metode Kempa Langsung
Review Jurnal: Evaluasi Kekerasan Sediaan Tablet Kunyah dengan Metode Kempa Langsung
Tablets are one of the most widely used forms of preparation on the market, one type of tablet preparation is chewable tablets. Chewable tablets are drugs that are consumed by chew...

Back to Top