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A practice survey on vasopressor and inotropic drug therapy in Scandinavian intensive care units

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Background: This practice survey was performed to analyse the indications for use of vasopressor/inotropic drugs, preferred drugs and doses as well as concomitant monitoring and desired haemodynamic target values in Scandinavian ICUs. An internet‐based reporting system was implemented.Methods: A total of 223 ICUs were identified in the Scandinavian countries and invited to participate in a one‐day point‐prevalence study. An internet‐based database was constructed and a practice survey protocol designed to identify haemodynamic monitoring, indications for vasopressor/inotropic drug‐therapy, fluids used for volume loading, pretreatment circulatory state, actual and targeted haemodynamic variables. Patients were eligible for the study if on vasopressor/inotropic drug‐therapy for more than 4 h.Results: A total of 114 ICUs participated. A total of 114 adult patients matched the inclusion criteria. Sixty‐seven per cent of the patients had received vasopressor/inotropic drug‐treatment for >24 h and 32% received more than one drug. Arterial hypotension (92%) and oliguria (50%) were most common indications. Fluid loading prior to therapy was reported in 87% of patients. Dopamine (47%) and noradrenaline (44%) were the most commonly used drugs followed by dobutamine (24%). No other drug exceeded 6%. Non‐catecholamine drugs were rarely used even in cardiac failure patients. Invasive arterial pressure was monitored in 95% of patients, pulmonary artery catheters were used in 19%. Other cardiac output monitoring techniques were used in 8.5% of the patients.Conclusion: Dopamine and noradrenaline seem to be the most commonly used inotropic/vasopressor drugs in Scandinavia. Traditional indications for inotropic/vasopressor support as hypotension and oliguria seem to be most common. Invasive monitoring was used in almost all patients, whereas a limited use of pulmonary artery catheters was noted. The internet‐based reporting system proved to be an efficient tool for data collection.
Title: A practice survey on vasopressor and inotropic drug therapy in Scandinavian intensive care units
Description:
Background: This practice survey was performed to analyse the indications for use of vasopressor/inotropic drugs, preferred drugs and doses as well as concomitant monitoring and desired haemodynamic target values in Scandinavian ICUs.
An internet‐based reporting system was implemented.
Methods: A total of 223 ICUs were identified in the Scandinavian countries and invited to participate in a one‐day point‐prevalence study.
An internet‐based database was constructed and a practice survey protocol designed to identify haemodynamic monitoring, indications for vasopressor/inotropic drug‐therapy, fluids used for volume loading, pretreatment circulatory state, actual and targeted haemodynamic variables.
Patients were eligible for the study if on vasopressor/inotropic drug‐therapy for more than 4 h.
Results: A total of 114 ICUs participated.
A total of 114 adult patients matched the inclusion criteria.
Sixty‐seven per cent of the patients had received vasopressor/inotropic drug‐treatment for >24 h and 32% received more than one drug.
Arterial hypotension (92%) and oliguria (50%) were most common indications.
Fluid loading prior to therapy was reported in 87% of patients.
Dopamine (47%) and noradrenaline (44%) were the most commonly used drugs followed by dobutamine (24%).
No other drug exceeded 6%.
Non‐catecholamine drugs were rarely used even in cardiac failure patients.
Invasive arterial pressure was monitored in 95% of patients, pulmonary artery catheters were used in 19%.
Other cardiac output monitoring techniques were used in 8.
5% of the patients.
Conclusion: Dopamine and noradrenaline seem to be the most commonly used inotropic/vasopressor drugs in Scandinavia.
Traditional indications for inotropic/vasopressor support as hypotension and oliguria seem to be most common.
Invasive monitoring was used in almost all patients, whereas a limited use of pulmonary artery catheters was noted.
The internet‐based reporting system proved to be an efficient tool for data collection.

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