Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Cardiac Amyloidosis
View through CrossRef
Amyloidosis represents a heterogeneous group of disorders caused by amyloid fibril deposition in the extracellular space in different organs. Among the many types of amyloidosis cardiac involvement occurs almost exclusively with immunoglobulin light chain amyloidosis (AL amyloidosis) or transthyretin amyloidosis (ATTR amyloidosis). When present cardiac amyloidosis (CA) has a significant impact on disease prognosis. The typical clinical presentation in CA is that of a restrictive cardiomyopathy. Clinical suspicion of CA is based on clinical, laboratory and electrocardiographic findings. The diagnosis is confirmed using echocardiography, cardiac magnetic resonance imaging, biopsy, and/or bone scintigraphy. A precise definition of amyloidosis type is essential for choosing the specific treatment for this condition. Treatment of CA has two components: general treatment of congestive HF, and specific treatment of the underlying protein misfolding disorder.
Title: Cardiac Amyloidosis
Description:
Amyloidosis represents a heterogeneous group of disorders caused by amyloid fibril deposition in the extracellular space in different organs.
Among the many types of amyloidosis cardiac involvement occurs almost exclusively with immunoglobulin light chain amyloidosis (AL amyloidosis) or transthyretin amyloidosis (ATTR amyloidosis).
When present cardiac amyloidosis (CA) has a significant impact on disease prognosis.
The typical clinical presentation in CA is that of a restrictive cardiomyopathy.
Clinical suspicion of CA is based on clinical, laboratory and electrocardiographic findings.
The diagnosis is confirmed using echocardiography, cardiac magnetic resonance imaging, biopsy, and/or bone scintigraphy.
A precise definition of amyloidosis type is essential for choosing the specific treatment for this condition.
Treatment of CA has two components: general treatment of congestive HF, and specific treatment of the underlying protein misfolding disorder.
Related Results
Anemia and outcome in cardiac amyloidosis
Anemia and outcome in cardiac amyloidosis
Abstract
Background
Anemia is a common comorbidity in patients with cardiac amyloidosis, yet its prognostic significance ...
Updates on Emerging Therapies in Cardiac Light Chain (AL) Amyloidosis
Updates on Emerging Therapies in Cardiac Light Chain (AL) Amyloidosis
Introduction:
Amyloidosis is a disorder where misfolded proteins get deposited in different tissues. The most common of them is immunoglobulin light chain (AL) depos...
Cardiomyopathies with left ventricular hypertrophy phenotype: prevalence of cardiac amyloidosis and clinical characteristics of patients
Cardiomyopathies with left ventricular hypertrophy phenotype: prevalence of cardiac amyloidosis and clinical characteristics of patients
Cardiac amyloidosis was long considered a rare disease, primarily affecting the elderly. However, recent studies have demonstrated a higher prevalence, highlighting the need for fu...
A Pilot Study of Rare Renal Amyloidosis Based on FFPE Proteomics
A Pilot Study of Rare Renal Amyloidosis Based on FFPE Proteomics
Renal amyloidosis typically manifests albuminuria, nephrotic-range proteinuria, and ultimately progresses to end-stage renal failure if diagnosed late. Different types of renal amy...
Comparative Histopathological Characteristics of Duodenal Involvement in Different Types of Amyloidosis
Comparative Histopathological Characteristics of Duodenal Involvement in Different Types of Amyloidosis
Background/Objectives: The duodenum is commonly involved in systemic amyloidosis. This retrospective observational study describes histoanatomical distributions of different types ...
Tổng quan bệnh tim thoái hóa dạng bột trong thực hành lâm sàng
Tổng quan bệnh tim thoái hóa dạng bột trong thực hành lâm sàng
Amyloidosis là một bệnh lý ảnh hưởng đến nhiều cơ quan do sự lắng đọng bất thường của các protein trong các mô khác nhau. Biểu hiện lâm sàng phụ thuộc vào thể bệnh và vị trí lắng đ...
Primary Amyloidosis Treated with Bortezomib with a Clinical and Radiological Response.
Primary Amyloidosis Treated with Bortezomib with a Clinical and Radiological Response.
Abstract
INTRODUCTION: Primary amyloidosis is a plasma cell dyscrasia related to multiple myeloma. The treatment for primary amyloidosis is very similar to the treat...
Hemodynamic, Functional and Structural Markers of Vascular Involvement in Primary Systemic Light Chain (AL) Amyloidosis
Hemodynamic, Functional and Structural Markers of Vascular Involvement in Primary Systemic Light Chain (AL) Amyloidosis
Abstract
Light chain (AL) amyloidosis is characterized by the extracellular deposition of clonal light chain-derived amyloid fibrils in various tissues. Kidneys and ...