Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Further extension of mammalian GATA‐6
View through CrossRef
Mammalian GATA‐6, which has conserved tandem zinc fingers (CVNC‐X17‐CNAC)‐X29‐(CXNC‐X17‐CNAC), is essential for the development and specific gene regulation of the heart, gastrointestinal tract and other tissues. GATA‐6 recognizes the (A/T/C)GAT(A/T)(A) sequence, and interacts with other transcriptional regulators through its zinc‐finger region. The mRNA of GATA‐6 uses two Met codons in frame as translational initiation codons, and produces L‐ and S‐type GATA‐6 through leaky ribosome scanning. GATA‐6 is subjected to cAMP‐dependent proteolysis by a proteasome in a heterologous expression system. These protein‐based characteristics of GATA‐6 will be helpful for the identification of target genes, together with determination of the in vivo binding sites for GATA‐6 and understanding of the complex network of gene regulation mediated by GATA‐6.
Title: Further extension of mammalian GATA‐6
Description:
Mammalian GATA‐6, which has conserved tandem zinc fingers (CVNC‐X17‐CNAC)‐X29‐(CXNC‐X17‐CNAC), is essential for the development and specific gene regulation of the heart, gastrointestinal tract and other tissues.
GATA‐6 recognizes the (A/T/C)GAT(A/T)(A) sequence, and interacts with other transcriptional regulators through its zinc‐finger region.
The mRNA of GATA‐6 uses two Met codons in frame as translational initiation codons, and produces L‐ and S‐type GATA‐6 through leaky ribosome scanning.
GATA‐6 is subjected to cAMP‐dependent proteolysis by a proteasome in a heterologous expression system.
These protein‐based characteristics of GATA‐6 will be helpful for the identification of target genes, together with determination of the in vivo binding sites for GATA‐6 and understanding of the complex network of gene regulation mediated by GATA‐6.
Related Results
Systematic Characterization of GATA Transcription Factors in Liriodendron chinense and Functional Validation in Abiotic Stresses
Systematic Characterization of GATA Transcription Factors in Liriodendron chinense and Functional Validation in Abiotic Stresses
The Liriodendron chinense in the Magnoliaceae family is an endangered tree species useful for its socio-economic and ecological benefits. Abiotic stresses (cold, heat, and drought ...
Genome-wide Survey of the GATA Gene Family in Camptothecin-producing Plant Ophiorrhiza Pumila
Genome-wide Survey of the GATA Gene Family in Camptothecin-producing Plant Ophiorrhiza Pumila
Abstract
Background: Ophiorrhiza pumila (Rubiaceae) is capable of producing camptothecin (CPT), one monoterpene indole alkaloid extensively employed in the treatment of mul...
A Seminar Title On the History and Evolution of Agricultural Extension in the Ethiopia Country
A Seminar Title On the History and Evolution of Agricultural Extension in the Ethiopia Country
Agricultural extension service began work in Ethiopia since 1931, during the establishment of Ambo Agricultural School. But a formal Agricultural extension started since Alemaya Im...
O “estado da arte” do ensino em Extensão Rural no Brasil
O “estado da arte” do ensino em Extensão Rural no Brasil
Este artigo tem como objetivo realizar uma análise do “estado da arte” do ensino em Extensão Rural no Brasil, considerando o panorama da oferta da disciplina, as tendências acadêmi...
Indução de parto distócico com Am-c em uma gata – Relato de caso
Indução de parto distócico com Am-c em uma gata – Relato de caso
Este artigo tem por objetivo relatar o uso da homeopatia em um caso de emergência de parto distócico em uma gata. O trabalho de parto demanda demasiada energia da mãe para o proces...
Immune Modulation Through Stereotactic Radiotherapy: The Role of TBX21, GATA-3, FoxP3, and RORɣt
Immune Modulation Through Stereotactic Radiotherapy: The Role of TBX21, GATA-3, FoxP3, and RORɣt
Background and Objectives: Stereotactic radiotherapy enhances local tumor control by delivering high doses directly to the tumor. It is thought to activate the immune system via T-...
LEVEL OF EXTENSION METHODS IMPORTANCE FROM THE AGRICULTURAL EXTENSION WORKERS POINT OF VIEW IN SULAIMANI GOVERNORATE
LEVEL OF EXTENSION METHODS IMPORTANCE FROM THE AGRICULTURAL EXTENSION WORKERS POINT OF VIEW IN SULAIMANI GOVERNORATE
The aim of this study was to determine the level of agricultural extension methods importance from the extension workers point of view in Sulaimani governorate, then identify relat...
Uma universidade possível à luz da extensão e da Educação Popular
Uma universidade possível à luz da extensão e da Educação Popular
Este artigo tem como objetivo trazer uma reflexão em torno da universidade brasileira em uma perspectiva histórico-crítica, a fim de apresentar um caminho possível para a elaboraçã...