Relationship between helicobacter pylori infection and the incidence of dyslipidemia among asymptomatic adults in Jimma City, Ethiopia

Abstract Infection with H. Pylori triggers chronic inflammatory states along with dyslipidemia contribute of atherosclerosis. However, there is lack of emerging evidences of relationship of H. pylori infections and dyslipidemia among healthy adults. Therefore, this study aimed to investigate the relationship between H. pylori infection and the incidence of dyslipidemia among asymptomatic adults in Jimma City, Ethiopia. A total of 865 asymptomatic adults aged > 18 years were enrolled in the study. From each study participants, 24-hrs dietary re-call, Rome-III based criteria abdominal pain symptoms, 5ml of venous blood and 20g of fresh stool was collected. From the study participants, positive H. pylori infection was, 170(19.7%) whereas dyslipidemia incidence was, 108(12.5). Factors significantly associated with the H. pylori positive test with an AOR (95% CI, p < 0.05) were chewing khat, less physical activity, dyslipidemia, being hypertensive, central obesity and functional dyspepsia as compared to their normal counterparts. However, H. pylori infection was not associated with any of the dietary diversity scores. H. pylori infection is detected among asymptomatic population living in our study area. Moreover, H. pylori infection is significantly associated with dyslipidemia. Therefore, early screening and decreasing the risk factors are highly recommendable.