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Therapeutic Validation of Coriandrum sativum Extract in Emesis and Analgesia
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In the traditional System of Medicine, the leaves and seeds of Coriandrum sativum are used usually as emollient, antii-flammatory, stom-achic, carmi-native, digestive, constipating, astringent, antipyretic, diuretic, appetizer, stimulant, refrigerant, tonic, expectorant, in dyspepsia etc. The aim of this study was to investigate antiemetic and analgesic activity of the whole plant extract of Coriandrum sativum in Wister albino rats and chick emesis models. The anti-emetic activity of the Coriandrum sativum is determined by using the chick emesis model. Antiemetic activity of Coriandrum sativum is determined by percentage inhibition of retching that is tempted with the help of copper sulfate. Copper sulphate is used to persuade emesis in chick. Analgesic activity is established by using the Wister albino rat as an experimental animal. Acetic acid is used to induce writhing in animals. The plant extract decreases the dose dependent writhing in acetic acid induced analgesia in Wister albino rats.
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Title: Therapeutic Validation of Coriandrum sativum Extract in Emesis and Analgesia
Description:
In the traditional System of Medicine, the leaves and seeds of Coriandrum sativum are used usually as emollient, antii-flammatory, stom-achic, carmi-native, digestive, constipating, astringent, antipyretic, diuretic, appetizer, stimulant, refrigerant, tonic, expectorant, in dyspepsia etc.
The aim of this study was to investigate antiemetic and analgesic activity of the whole plant extract of Coriandrum sativum in Wister albino rats and chick emesis models.
The anti-emetic activity of the Coriandrum sativum is determined by using the chick emesis model.
Antiemetic activity of Coriandrum sativum is determined by percentage inhibition of retching that is tempted with the help of copper sulfate.
Copper sulphate is used to persuade emesis in chick.
Analgesic activity is established by using the Wister albino rat as an experimental animal.
Acetic acid is used to induce writhing in animals.
The plant extract decreases the dose dependent writhing in acetic acid induced analgesia in Wister albino rats.
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