Examining the Anxiolytic Effects of Flavonoids in Passionflower: A Gut-Brain Axis Perspective

This literature review investigates the influence of Passiflora incarnata on the Gut-Brain Axis, focusing on the role of flavonoids and the specific biological mechanisms involved in this process. The study aims to identify Passiflora incarnata as a practical, non-harmful, and cost-effective alternative to current modern anxiety medications. This study also emphasizes the need for further clinical trials to integrate Passiflora incarnata further into healthcare settings. Using a narrative review approach, this analysis will examine pre-existing empirical articles, all of which have been found on credible sites, are peer-reviewed, and have been published within the past twenty-five years. The data discussed in this review will be analyzed to determine if the hypothesized relationships exist and their practical significance. If supported, the hypothesis validates the theory that Passiflora incarnata alleviates anxiety in part by modulating the Gut-Brain Axis, emphasizing the need for further clinical investigations.