InterProScan: Protein sequence analysis and classification

InterPro (http://www.ebi.ac.uk/interpro/) is a freely available resource that is used to classify sequences into protein families and to predict the presence of important domains and sites. InterProScan (https://www.ebi.ac.uk/interpro/interproscan.html) is the underlying software application that allows both protein and nucleic acid sequences to be scanned against InterPro's predictive models (profile hidden Markov models, profiles, position-specific scoring matrices and regular expressions), which are provided by the resource’s member databases. Here, we present recent developments which include support for specific functional inferences provided by new per-residue annotations and prediction of intrinsically disordered regions.