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Predischarge Screening of Neonates with Transcutaneous Bilirubinometer
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Objective:
To compare the diagnostic accuracy of various transcutaneous bilirubin (TcB) nomograms for predischarge screening.
Methods:
The paired total serum bilirubin (TSB) and TcB measurements collected in neonates ≥35 weeks and ≥2000 g birth weight were analyzed. BiliCare™ bilirubinometer was used for TcB measurement. We chose the following nomograms for the study: Bhutani nomogram, Maisel's nomogram, Agarwal nomogram, Thakkar nomogram, American Academy of Pediatrics (AAP) nomogram within 3 mg/dl of phototherapy cutoff, AAP nomogram >70% of phototherapy cutoff and if TcB value is above 13 mg/dl. The diagnostic accuracy of these nomograms for TcB was compared with TSB plotted in the Bhutani nomogram.
Results:
TcB showed a positive correlation with TSB (Pearson correlation coefficient = 0.783). Bhutani nomogram, Maisel's nomogram and AAP (using within 3 mg/dL cutoff) nomogram showed good sensitivity and low false-negative rate while avoiding blood draws in most neonates.
Conclusion:
Bhutani nomogram, Maisel's nomogram, and AAP (using within 3 mg/dL of phototherapy cutoff) nomograms have comparable diagnostic accuracy for predischarge bilirubin screening in neonates.
Ovid Technologies (Wolters Kluwer Health)
Title: Predischarge Screening of Neonates with Transcutaneous Bilirubinometer
Description:
Objective:
To compare the diagnostic accuracy of various transcutaneous bilirubin (TcB) nomograms for predischarge screening.
Methods:
The paired total serum bilirubin (TSB) and TcB measurements collected in neonates ≥35 weeks and ≥2000 g birth weight were analyzed.
BiliCare™ bilirubinometer was used for TcB measurement.
We chose the following nomograms for the study: Bhutani nomogram, Maisel's nomogram, Agarwal nomogram, Thakkar nomogram, American Academy of Pediatrics (AAP) nomogram within 3 mg/dl of phototherapy cutoff, AAP nomogram >70% of phototherapy cutoff and if TcB value is above 13 mg/dl.
The diagnostic accuracy of these nomograms for TcB was compared with TSB plotted in the Bhutani nomogram.
Results:
TcB showed a positive correlation with TSB (Pearson correlation coefficient = 0.
783).
Bhutani nomogram, Maisel's nomogram and AAP (using within 3 mg/dL cutoff) nomogram showed good sensitivity and low false-negative rate while avoiding blood draws in most neonates.
Conclusion:
Bhutani nomogram, Maisel's nomogram, and AAP (using within 3 mg/dL of phototherapy cutoff) nomograms have comparable diagnostic accuracy for predischarge bilirubin screening in neonates.
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