The study some changes biochemical parameters in patient’s renal failure in before and after haemodialysis program

          This study was designed to investigate changes in some biochemical parameters (urea, creatinine, sodium, potassium) at the end stage of renal disease (ESRD) patient on convenintial haemodialysis program.          The study was included collected of one hundred and thirteen (113) samples. Eighty-three (83) patients with end stage renal disease on haemodialysis program including (47) males and (36) females with a mean age of (43.3±18.0) years and range from (20-65) years. All the patients had been on dialysis twice per week for two hours each time. In addition, thirty from apparently healthy volunteers as control.          The subjects were fasted for twelve hours and the samples were drowning 30 minutes before haemodialysis and 30 minutes after haemodialysis.         This study showed highly significant differences in urea and creatinine concentrations before and after haemodialysis and when compared with control (before haemodialysis with control and after haemodialysis with control). The significant changes exist when the patients grouped according to gender (male and female) and age [(20-35), (36-50) and (51-65) years].         The electrolytes were varied in their changes. There was non-significant difference in sodium concentration except significant change in before and after haemodialysis when compared each with control; while potassium showed a highly significant changes except when pre dialysis compared to control and in the last two age groups (36-50) and (51-65) years in which there were no significant difference.