Bio-accessibility of Pre-synthesized Abhrak, Naga and Tamra Bhasma

Ayurvedic bhasmas play an important role in ayurvedic medicines and are useful in the treatment of various diseases. Pharmacokinetic studies involving estimation of bio accessibility of bhasma will be useful in prescribing proper dosage of bhasma. Present paper deals with bio-accessibility of Abhraka, Naga and Tamra Bhasmas which were synthesized in our laboratory. It is revealed that the bio-accessibility of elements viz. K, Ca, Al, Fe, Na and Si in abhraka bhasma is more in gastric digestion than in gastro-intestinal digestion. Bio accessibility of lead was found to be more in gastric digestion than gastro-intestinal digestion in Naga bhasma prepared by pisti and putapaka method while in bhasma prepared by jarana method it is more in gastro-intestinal digestion. In case of Tamra bhasma, bio-accessibility of copper is more in Gastro-intestinal digestion and it is further enhanced with anupana process, especially using ghee.