Reproducibility of Ocular Biometry and Pupillometry with the Aladdin HW2.0 Optical Low-Coherence Interferometer

Objective: The purpose of the study was to evaluate the reproducibility of ocular biometry and pupillometry with the Aladdin HW2.0 (Topcon, Tokyo, Japan) in patients with cataracts and healthy subjects.Materials and Methods: This prospective study was performed in eyes of healthy subjects and patients with cataracts. After a full ophthalmological examination; axial length (AL), anterior chamber depth (ACD), keratometry (K values), white-to-white (WTW), intraocular lens (IOL) powers, and pupillometric parameters were measured with the Aladdin biometer by two operators.Results: 72 eyes of 40 patients with cataracts and 57 eyes of 29 healthy subjects were evaluated. AL, ACD, K values, WTW and IOL power formulas were highly reproducible [intraclass correlation coefficient (ICC)>0.900] in two groups. AL was the most reproducible parameter in patients with cataracts, ACD in the healthy subjects. The ICC values of pupillometry were lower than 0.900 (range from 0.100 to 0.882) in patients with cataracts. The worst reproducible parameter was the maximum diameter of dynamic pupillometry. Except for the photopic pupil diameter from the healthy group, pupillometry parameters were within a quite wide range for 95% LoA.Conclusion: The Aladdin HW2.0 optical low coherence interferometer showed excellent inter-operator reproducibility for AL, ACD, K values, WTW and IOL power formulas except for pupillometry measurements.