Phytochemical Screening, GC-MS Study, FTIR analysis and antimicrobial activities of ethanol extracts of Tetrapleura tetraptera fruit

Introduction: Antimicrobial and phytochemical properties have been associated with the therapeutic effects of plants. This study aimed to qualitatively assess the Tetrapleura tetraptera fruit ethanol extract for phytoconstituents. Method: The extract was subjected to GC-MS and FTIR analysis to identify bioactive components and functional groups. The Mycelial Inhibition Method was employed to evaluate the extract's antifungal properties against selected microorganisms. In the phytochemical screening, the ethanol extract exhibited the presence of all examined phytochemicals. Results: GC-MS analysis revealed 15 compounds from 6 recognized classes, with Ethyl Oleate (48.21%), 9-Octadecenoic acid, (E)- (19.18%), 9-Oxabicyclo [6.1.0] nonane, cis- (8.86%), Hexadecanoic acid, ethyl ester (6.24%), and 9,12-Octadecadienoic acid, ethyl ester (4.46%) being the principal chemical components. Results from FTIR analysis indicated significant chemical functional groups in the ethanol extract. Moreover, the extract demonstrated enhanced antimicrobial activity compared to the control, suggesting its potential therapeutic applications. Conclusion: These findings imply that Tetrapleura tetraptera could serve as a source of bioactive substances.