Biological Activity of Fruits, Leaves, Trunk Bark and Seeds of Tetrapleura tetraptera Used in Vaginal and Intestinal Infections

Traditional medicine treats various diseases, in particular vaginal and intestinal infections, usually using plant species. This study aims to study the photochemistry, the antiradical activity and the antimicrobial activity of Tetrapleura tetraptera. Qualitative phytochemical analyzes were performed using standard colorimetric methods. Flavonoids were quantified relative to the reference molecule. The antiradical activity was evaluated by the phosphomolybdate reduction method and the iron reduction method. The antimicrobial activity was carried out using the agar diffusion method. Tetrapleura tetraptera species showed phytochemical compositions with bioactive potentials. Extracts of fruits, leaves, trunk bark and seeds of Tetrapleura tetraptera have been shown to be rich in phenolic compounds, alkaloids, tannins and reducing sugars. These extracts also have flavonoid contents with values from 71.470 ± 2.258 to 147.196 ± 1.529 μg ER/mg ES. The extracts showed antiradical activity with contents ranging from 81.093 ± 1.736 to 128.695 ± 4.589 mg EAA/g ES for the phosphomolybdate reduction method and from 200.500 ± 0.000 to 322.167 ± 21.213 μmol Eq FeS04/mg ES for the method of iron reduction. Antimicrobial tests have shown that these tested extracts variously inhibit the growth of the germs used apart from strains of Klebsiella pneumoniae and Klebsiella oxytoca. The minimal inhibitory concentrations varied from 3.125 to 50 mg/ml and the minimal bactericidal concentrations also varied from 3.125 to 50 mg/ml. The species Tetrapleura tetraptera has several phytochemicals. It has good antiradical activity and has shown antimicrobial activity on certain strains.